Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | PRKCA | P17252 | 2/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3425777 | 1.00 | ALOX5 (0.58) | ALOX5TSHRTRPV1PRKCAPRKCE | |
| SCHEMBL10058627 | 1.00 | ALOX5 (0.58) | ALOX5TSHRTRPV1PRKCAPRKCE | |
| SCHEMBL4813968 | 0.95 | ALOX5 (0.57) | ALOX5TSHRTRPV1PRKCAPRKCE | |
| Cyclopropane SCHEMBL20558634 | 0.92 | ALOX5 (0.54) | ALOX5TSHRTRPV1PRKCAPRKCE | |
| SCHEMBL10085305 | 0.90 | ALOX5 (0.62) | ALOX5TSHRTRPV1HPSECA12 | |
| SCHEMBL16174233 | 0.90 | ALOX5 (0.62) | ALOX5TSHRTRPV1HPSECA12 | |
| SCHEMBL2505317 | 0.90 | ALOX5 (0.62) | ALOX5TSHRTRPV1HPSECA12 | |
| SCHEMBL31039608 | 0.90 | ALOX5 (0.62) | ALOX5TSHRTRPV1HPSECA12 | |
| SCHEMBL2508699 | 0.90 | ALOX5 (0.62) | ALOX5TSHRTRPV1HPSECA12 | |
| SCHEMBL2505318 | 0.90 | ALOX5 (0.62) | ALOX5TSHRTRPV1HPSECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012006510-A1 | FATTY ACID PROTEIN KINASE C ACTIVATORS AND ANTICOAGULANT FOR THE TREATMENT OF STROKE | ALKON DANIEL L (US) | 2012-01-12 | — | — | WO | disclosed |