Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | PRKCA | P17252 | 2/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3425777 | 1.00 | ALOX5 (0.58) | ALOX5TSHRTRPV1PRKCAPRKCE | |
| SCHEMBL10057523 | 1.00 | ALOX5 (0.58) | ALOX5TSHRTRPV1PRKCAPRKCE | |
| SCHEMBL4813968 | 0.95 | ALOX5 (0.57) | ALOX5TSHRTRPV1PRKCAPRKCE | |
| Cyclopropane SCHEMBL20558634 | 0.92 | ALOX5 (0.54) | ALOX5TSHRTRPV1PRKCAPRKCE | |
| SCHEMBL10085305 | 0.90 | ALOX5 (0.62) | ALOX5TSHRTRPV1HPSECA12 | |
| SCHEMBL16174233 | 0.90 | ALOX5 (0.62) | ALOX5TSHRTRPV1HPSECA12 | |
| SCHEMBL2505317 | 0.90 | ALOX5 (0.62) | ALOX5TSHRTRPV1HPSECA12 | |
| SCHEMBL31039608 | 0.90 | ALOX5 (0.62) | ALOX5TSHRTRPV1HPSECA12 | |
| SCHEMBL2508699 | 0.90 | ALOX5 (0.62) | ALOX5TSHRTRPV1HPSECA12 | |
| SCHEMBL2505318 | 0.90 | ALOX5 (0.62) | ALOX5TSHRTRPV1HPSECA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120027687-A1 | FATTY ACID PROTEIN KINASE C ACTIVATORS AND ANTICOAGULANT FOR THE TREATMENT OF STROKE | WEST VIRGINIA UNIVERSITY | 2012-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120027687-A1 | FATTY ACID PROTEIN KINASE C ACTIVATORS AND ANTICOAGULANT FOR THE TREATMENT OF STROKE | PRKCA, FABP7, PRKCZ | ALOX5 174/4885TSHR 1203/4885TRPV1 2428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.