Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 3/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.35 |
| ▸ | RARG | P13631 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 8/20 | 0.35 |
| ▸ | GRK6 | P43250 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10057972 | 0.96 | PDK2 (0.36) | RARBRARGRXRAPDK2GRK6 | |
| SCHEMBL10057962 | 0.95 | PTPRC (0.36) | PTPRCPTPN1RARBRARGRXRA | |
| SCHEMBL30345763 | 0.89 | PDK2 (0.40) | RARBRARGRXRAPDK2 | |
| SCHEMBL5459081 | 0.89 | PDK2 (0.40) | RARBRARGRXRAPDK2 | |
| SCHEMBL10057545 | 0.88 | MEN1 (0.38) | PTPRCPTPN1PDK2PGRMEN1 | |
| SCHEMBL10057973 | 0.86 | NPC1 (0.39) | PTPRCPTPN1PDK2PGRMEN1 | |
| SCHEMBL10057537 | 0.82 | MEN1 (0.43) | RARBRARGPDK2PGRMEN1 | |
| SCHEMBL10057457 | 0.82 | MEN1 (0.39) | PTPRCPTPN1PDK2PGRMEN1 | |
| SCHEMBL10057531 | 0.81 | MEN1 (0.50) | PTPN1PDK2PGRMEN1APAF1 | |
| SCHEMBL10057536 | 0.81 | MEN1 (0.50) | PTPN1PDK2PGRMEN1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130105786-A1 | NOVEL SPIRO(ANTHRACENE-9,9'-FLUOREN)-10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2013-05-02 | — | — | US | disclosed |
| US-20130105786-A1 | NOVEL SPIRO(ANTHRACENE-9,9'-FLUOREN)-10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2013-05-02 | — | — | US | disclosed |
| WO-2012008557-A1 | NOVEL SPIRO (ANTHRACENE-9,9'-FLUOREN) -10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-01-19 | — | — | WO | disclosed |