Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GALK1 | P51570 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 11/20 | 0.37 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10057545 | 0.99 | MEN1 (0.38) | NPC1RAB9ASMN1; SMN2MEN1APAF1 | |
| SCHEMBL10057982 | 0.93 | MEN1 (0.44) | NPC1RAB9ASMN1; SMN2MEN1APAF1 | |
| SCHEMBL12177771 | 0.92 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2MEN1APAF1 | |
| SCHEMBL10057457 | 0.92 | MEN1 (0.39) | NPC1RAB9ASMN1; SMN2MEN1APAF1 | |
| SCHEMBL10057537 | 0.92 | MEN1 (0.43) | NPC1RAB9ASMN1; SMN2MEN1APAF1 | |
| SCHEMBL12177773 | 0.88 | MEN1 (0.43) | NPC1RAB9ASMN1; SMN2MEN1APAF1 | |
| SCHEMBL12177813 | 0.88 | MEN1 (0.42) | NPC1RAB9ASMN1; SMN2MEN1APAF1 | |
| SCHEMBL14702110 | 0.88 | PDK2 (0.42) | NPC1RAB9ASMN1; SMN2MEN1APAF1 | |
| SCHEMBL10057539 | 0.86 | PTPRC (0.36) | NPC1RAB9ASMN1; SMN2MEN1APAF1 | |
| SCHEMBL10057458 | 0.86 | MEN1 (0.44) | NPC1RAB9ASMN1; SMN2MEN1APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130105786-A1 | NOVEL SPIRO(ANTHRACENE-9,9'-FLUOREN)-10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2013-05-02 | — | — | US | disclosed |
| US-20130105786-A1 | NOVEL SPIRO(ANTHRACENE-9,9'-FLUOREN)-10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2013-05-02 | — | — | US | disclosed |
| WO-2012008557-A1 | NOVEL SPIRO (ANTHRACENE-9,9'-FLUOREN) -10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-01-19 | — | — | WO | disclosed |