Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GALK1 | P51570 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 13/20 | 0.36 |
| ▸ | PTPRC | P08575 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10057973 | 0.99 | NPC1 (0.39) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL10057457 | 0.94 | MEN1 (0.39) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL10057537 | 0.94 | MEN1 (0.43) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL10057982 | 0.92 | MEN1 (0.44) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL12177771 | 0.91 | NPC1 (0.42) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL12177773 | 0.90 | MEN1 (0.43) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL12177813 | 0.89 | MEN1 (0.42) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL10057539 | 0.88 | PTPRC (0.36) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL10057458 | 0.87 | MEN1 (0.44) | MEN1APAF1NPC1LMNAMAPT | |
| SCHEMBL12177884 | 0.87 | MEN1 (0.42) | MEN1APAF1NPC1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160308129-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-10-20 | — | — | US | disclosed |
| US-20160308129-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2016-10-20 | — | — | US | disclosed |
| US-20130105786-A1 | NOVEL SPIRO(ANTHRACENE-9,9'-FLUOREN)-10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2013-05-02 | — | — | US | disclosed |
| US-20130105786-A1 | NOVEL SPIRO(ANTHRACENE-9,9'-FLUOREN)-10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2013-05-02 | — | — | US | disclosed |
| WO-2012008557-A1 | NOVEL SPIRO (ANTHRACENE-9,9'-FLUOREN) -10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-01-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160308129-A1 | MATERIALS FOR ELECTRONIC DEVICES | EFNA1, GPX1, EPN1 | MEN1 465/4885APAF1 3976/4885NPC1 2720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.