Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | METAP1 | P53582 | 2/20 | 0.49 |
| ▸ | S100A4 | P26447 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | ROS1 | P08922 | 1/20 | 0.41 |
| ▸ | MARK3 | P27448 | 1/20 | 0.41 |
| ▸ | LTK | P29376 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | PBK | Q96KB5 | 1/20 | 0.41 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10057541 | 0.84 | TDP1 (0.63) | TDP1L3MBTL1METAP1S100A4TDP2 | |
| SCHEMBL8206319 | 0.80 | TDP1 (0.55) | TDP1L3MBTL1METAP1S100A4TDP2 | |
| SCHEMBL27761880 | 0.78 | METAP1 (0.65) | TDP1L3MBTL1METAP1S100A4TDP2 | |
| SCHEMBL27456249 | 0.77 | PARP1 (0.43) | METAP1TDP2PARP1PARP10CA1 | |
| SCHEMBL21547664 | 0.77 | TDP2 (0.51) | METAP1TDP2TGM2CES1MAOA | |
| SCHEMBL31073 | 0.77 | METAP1 (0.79) | TDP1L3MBTL1METAP1S100A4TDP2 | |
| SCHEMBL27456260 | 0.77 | METAP1 (0.62) | METAP1PARP1PARP10CA1CA2 | |
| SCHEMBL394145 | 0.76 | TDP1 (0.80) | TDP1L3MBTL1METAP1S100A4PTPRC | |
| SCHEMBL2370367 | 0.75 | METAP1 (0.50) | TDP1L3MBTL1METAP1S100A4TDP2 | |
| SCHEMBL358939 | 0.75 | TDP1 (0.81) | TDP1L3MBTL1METAP1S100A4TDP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023132606-A1 | NOVEL ISOINDOLINONE DERIVATIVE COMPOUNDS AS CASPASE INHIBITORS | 주식회사 이노보테라퓨틱스 | 2023-07-13 | — | — | WO | disclosed |