SCHEMBL27761880

SCHEMBL27761880

O=C1c2ccc(Br)cc2Cc2ccc(Br)cc21

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
METAP1 P53582 1/20 0.65
TDP1 Q9NUW8 1/20 0.62
L3MBTL1 Q9Y468 1/20 0.62
S100A4 P26447 1/20 0.54
TDP2 O95551 2/20 0.53
BCL2 P10415 2/20 0.50
MCL1 Q07820 1/20 0.50
MAOA P21397 3/20 0.48
PTPRC P08575 1/20 0.47
MAOB P27338 2/20 0.46
CHEK2 O96017 1/20 0.46
ROS1 P08922 1/20 0.46
MARK3 P27448 1/20 0.46
LTK P29376 1/20 0.46
FLT4 P35916 1/20 0.46
KDR P35968 1/20 0.46
MINK1 Q8N4C8 1/20 0.46
AURKB Q96GD4 1/20 0.46
PBK Q96KB5 1/20 0.46
STK17A Q9UEE5 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10057541 0.94 TDP1 (0.63) METAP1TDP1L3MBTL1S100A4TDP2
SCHEMBL4254618 0.94 METAP1 (0.71) METAP1TDP1L3MBTL1S100A4TDP2
SCHEMBL394145 0.89 TDP1 (0.80) METAP1TDP1L3MBTL1S100A4BCL2
SCHEMBL10692517 0.88 METAP1 (0.56) METAP1TDP1L3MBTL1S100A4TDP2
SCHEMBL22797539 0.86 TDP1 (0.77) METAP1TDP1L3MBTL1S100A4TDP2
SCHEMBL3129344 0.83 METAP1 (0.52) METAP1TDP1L3MBTL1S100A4TDP2
SCHEMBL28360994 0.83 METAP1 (0.52) METAP1TDP1L3MBTL1S100A4TDP2
SCHEMBL29569917 0.83 METAP1 (0.52) METAP1TDP1L3MBTL1S100A4TDP2
SCHEMBL11140043 0.82 TDP1 (0.75) METAP1TDP1L3MBTL1S100A4TDP2
SCHEMBL8206319 0.82 TDP1 (0.55) METAP1TDP1L3MBTL1S100A4TDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101570504-B Novel compounds for electronic material and organic electronic device using the same GRACEL DISPLAY INC 2013-07-24 CN disclosed
CN-101570504-A Novel compounds for electronic material and organic electronic device using the same GRACEL DISPLAY INC (KR) 2009-11-04 CN disclosed