Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | XBP1 | P17861 | 1/20 | 0.44 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GALK1 | P51570 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10057589 | 0.91 | NPC1 (0.51) | L3MBTL1MEN1APAF1NPC1LMNA | |
| SCHEMBL10057461 | 0.90 | THRB (0.50) | L3MBTL1MEN1APAF1NPC1LMNA | |
| SCHEMBL10057591 | 0.88 | THRB (0.51) | L3MBTL1MEN1APAF1NPC1LMNA | |
| SCHEMBL10057462 | 0.88 | THRB (0.51) | L3MBTL1MEN1APAF1NPC1LMNA | |
| SCHEMBL22797311 | 0.88 | MAPK1 (0.45) | L3MBTL1MEN1APAF1NPC1LMNA | |
| SCHEMBL26369373 | 0.88 | MAPK1 (0.45) | L3MBTL1MEN1APAF1NPC1LMNA | |
| SCHEMBL10057590 | 0.88 | MEN1 (0.55) | L3MBTL1MEN1APAF1NPC1LMNA | |
| SCHEMBL10057464 | 0.88 | L3MBTL1 (0.43) | L3MBTL1MEN1APAF1NPC1LMNA | |
| SCHEMBL10057544 | 0.87 | TDP1 (0.54) | L3MBTL1MEN1KMT2ATDP1PTPRC | |
| SCHEMBL10057533 | 0.86 | MEN1 (0.50) | L3MBTL1MEN1APAF1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130105786-A1 | NOVEL SPIRO(ANTHRACENE-9,9'-FLUOREN)-10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2013-05-02 | — | — | US | disclosed |
| US-20130105786-A1 | NOVEL SPIRO(ANTHRACENE-9,9'-FLUOREN)-10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2013-05-02 | — | — | US | disclosed |
| WO-2012008557-A1 | NOVEL SPIRO (ANTHRACENE-9,9'-FLUOREN) -10-ONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | CANON KABUSHIKI KAISHA (JP) | 2012-01-19 | — | — | WO | disclosed |