Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10077965 | 0.82 | TDO2 (0.43) | HRH3 | |
| SCHEMBL20069050 | 0.82 | OGA (0.52) | HRH3OGA | |
| SCHEMBL20147458 | 0.82 | HRH3 (0.56) | HRH3 | |
| SCHEMBL20147450 | 0.78 | HRH3 (0.51) | HRH3 | |
| SCHEMBL20147440 | 0.75 | HRH3 (0.48) | HRH3 | |
| SCHEMBL2541563 | 0.74 | HRH3 (0.64) | HRH3 | |
| SCHEMBL6123521 | 0.74 | HRH3 (0.54) | HRH3 | |
| SCHEMBL14423906 | 0.74 | HRH3 (0.66) | HRH3 | |
| SCHEMBL20152055 | 0.74 | HRH3 (0.48) | HRH3 | |
| SCHEMBL19862569 | 0.74 | HRH3 (0.48) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148404-B2 | Modulators of CB1 receptors | 7TM PHARMA A/S (DK) | 2012-04-03 | — | — | US | disclosed |
| US-20100144701-A1 | Modulators of CB1 Receptors | 7TM PHARMA A/S (DK) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144701-A1 | Modulators of CB1 Receptors | CNR1, CNR2, GPR6 | HRH3 127/4885OGA 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.