Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19764133 | 0.83 | HRH3 (0.44) | LRRK2HRH3SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL10057701 | 0.82 | HRH3 (0.45) | HRH3 | |
| SCHEMBL12929421 | 0.80 | LRRK2 (0.48) | LRRK2HRH3SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL20147962 | 0.79 | TDO2 (0.61) | TDO2HRH3SMN1; SMN2MAPT | |
| SCHEMBL995078 | 0.77 | HRH3 (0.45) | LRRK2HRH3SMN1; SMN2CHRM2CHRM4 | |
| SCHEMBL19764135 | 0.76 | MAPT (0.42) | LRRK2HRH3MAPT | |
| SCHEMBL940760 | 0.75 | HRH1 (0.43) | TDO2CHRM3 | |
| SCHEMBL20069132 | 0.75 | HRH3 (0.46) | LRRK2HRH3SMN1; SMN2CHRM4 | |
| SCHEMBL13873153 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2 | |
| SCHEMBL23405944 | 0.73 | GSK3B (0.43) | LRRK2HRH3SMN1; SMN2CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8148404-B2 | Modulators of CB1 receptors | 7TM PHARMA A/S (DK) | 2012-04-03 | — | — | US | disclosed |
| US-20100144701-A1 | Modulators of CB1 Receptors | 7TM PHARMA A/S (DK) | 2010-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144701-A1 | Modulators of CB1 Receptors | CNR1, CNR2, GPR6 | TDO2 2387/4885LRRK2 3118/4885HRH3 127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.