SCHEMBL10057795

SCHEMBL10057795

COc1ccc(N(c2ccc(OC)cc2)c2ccc(-c3ccc(N(c4ccc(-c5ccc(N(c6ccc(-c7ccc(N(c8ccc(OC)cc8)c8ccc(OC)cc8)cc7)cc6)c6ccc(C(C)(C)C)cc6)cc5)cc4)c4ccc(C(C)(C)C)cc4)cc3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.49
ALDH1A1 P00352 4/20 0.47
MAPK1 P28482 3/20 0.47
LMNA P02545 2/20 0.47
HSD17B10 Q99714 2/20 0.47
ALOX15 P16050 1/20 0.47
APEX1 P27695 1/20 0.47
RECQL P46063 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
HSP90AA1 P07900 1/20 0.44
HSP90AB1 P08238 1/20 0.44
ESR2 Q92731 1/20 0.44
KIF11 P52732 2/20 0.42
APP P05067 1/20 0.42
TP53 P04637 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
MEN1 O00255 1/20 0.42
EPHX2 P34913 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23866680 1.00 MAPT (0.49) MAPTALDH1A1MAPK1LMNAHSD17B10
SCHEMBL23866681 0.95 ALDH1A1 (0.49) MAPTALDH1A1MAPK1LMNAHSD17B10
SCHEMBL12606779 0.93 NPSR1 (0.47) MAPTALDH1A1MAPK1LMNAHSD17B10
SCHEMBL10025023 0.93 TSHR (0.48) MAPTALDH1A1MAPK1LMNAHSD17B10
SCHEMBL2608411 0.88 MAPT (0.58) MAPTALDH1A1MAPK1LMNAHSD17B10
SCHEMBL2511345 0.86 ESR2 (0.56) MAPTALDH1A1MAPK1HSD17B10TDP1
SCHEMBL10057879 0.86 ESR2 (0.56) MAPTALDH1A1MAPK1HSD17B10TDP1
SCHEMBL2213226 0.86 ESR2 (0.56) MAPTALDH1A1MAPK1HSD17B10TDP1
SCHEMBL10057657 0.86 ESR2 (0.56) MAPTALDH1A1MAPK1HSD17B10TDP1
SCHEMBL10057769 0.86 ESR2 (0.56) MAPTALDH1A1MAPK1HSD17B10TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2596509-B1 DYE SOLAR CELL WITH IMPROVED STABILITY BASF SE (DE) 2019-06-19 EP disclosed
US-20170082426-A1 DETECTOR FOR OPTICALLY DETECTING AT LEAST ONE OBJECT BASF SE (DE) 2017-03-23 US disclosed
US-9595678-B2 Dye solar cell with improved stability BASF SE (DE) 2017-03-14 US disclosed
EP-3029485-A1 DETECTOR FOR OPTICALLY DETECTING AT LEAST ONE OBJECT BASF SE (DE) 2016-06-08 EP disclosed
EP-2676102-B1 DETECTOR FOR OPTICALLY DETECTING AT LEAST ONE OBJECT BASF SE (DE) 2016-04-20 EP disclosed
US-9087991-B2 Photovoltaic element BASF SE (DE) 2015-07-21 US disclosed
US-20150124268-A1 DETECTOR FOR OPTICALLY DETECTING AT LEAST ONE OBJECT BASF SE (DE) 2015-05-07 US disclosed
US-9001029-B2 Detector for optically detecting at least one object BASF SE (DE) 2015-04-07 US disclosed
US-20140130870-A1 USE OF TRIARYLAMINE DERIVATIVES AS HOLE-CONDUCTING MATERIALS IN ORGANIC SOLAR CELLS AND ORGANIC SOLAR CELLS CONTAINING SAID TRIARYLAMINE DERIVATIVES BASF SE (DE) 2014-05-15 US disclosed
US-20120279566-A1 PHOTOVOLTAIC ELEMENT WITH INCREASED LONG-TERM STABILITY BASF SE (DE) 2012-11-08 US disclosed
WO-2012110924-A1 DETECTOR FOR OPTICALLY DETECTING AT LEAST ONE OBJECT BASF SE (DE) 2012-08-23 WO disclosed
US-20120206336-A1 DETECTOR FOR OPTICALLY DETECTING AT LEAST ONE OBJECT BASF SE (DE) 2012-08-16 US disclosed
US-20120192945-A1 PHOTOVOLTAIC ELEMENT BASF SE (DE) 2012-08-02 US disclosed
US-20120017995-A1 DYE SOLAR CELL WITH IMPROVED STABILITY BASF SE (DE) 2012-01-26 US disclosed
WO-2012011023-A2 DYE SOLAR CELL WITH IMPROVED STABILITY BASF SE (DE) 2012-01-26 WO disclosed
US-20110297235-A1 USE OF TRIARYLAMINE DERIVATIVES AS HOLE-CONDUCTING MATERIALS IN ORGANIC SOLAR CELLS AND ORGANIC SOLAR CELLS CONTAINING SAID TRIARYLAMINE DERIVATIVES BASF SE (DE) 2011-12-08 US disclosed
WO-2010094636-A1 USE OF TRIARYLAMINE DERIVATIVES AS HOLE-CONDUCTING MATERIALS IN ORGANIC SOLAR CELLS AND ORGANIC SOLAR CELLS CONTAINING SAID TRIARYLAMINE DERIVATIVES BASF SE (DE) 2010-08-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110297235-A1 USE OF TRIARYLAMINE DERIVATIVES AS HOLE-CONDUCTING MATERIALS IN ORGANIC SOLAR CELLS AND ORGANIC SOLAR CELLS CONTAINING SAID TRIARYLAMINE DERIVATIVES NR2E3, NR0B2, AHR MAPT 3648/4885ALDH1A1 1407/4885MAPK1 3579/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.