⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL104277 | 0.97 | — | — | |
| SCHEMBL6584212 | 0.97 | — | — | |
| SCHEMBL101996 | 0.90 | — | — | |
| SCHEMBL8763215 | 0.71 | — | — | |
| SCHEMBL8763991 | 0.69 | ALDH1A1 (0.39) | — | |
| SCHEMBL8763984 | 0.69 | ALDH1A1 (0.39) | — | |
| SCHEMBL8763101 | 0.69 | — | — | |
| SCHEMBL8763092 | 0.69 | — | — | |
| SCHEMBL8462648 | 0.65 | — | — | |
| SCHEMBL1672492 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 717 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118164874-A | Method for synthesizing chiral aryl compound based on unsaturated hydrocarbon, oxime ester and arylboronic acid | 华中师范大学 | 2024-06-11 | — | — | CN | claimed |
| CN-117886814-A | PD-1/PD-L1 small molecule inhibitor and application thereof in medicines | 广东东阳光药业股份有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-115974713-A | Fluorine-containing compound, preparation method and compound containing fluorine-containing compound | 中国科学技术大学 | 2023-04-18 | — | — | CN | claimed |
| CN-115232109-A | PD-1/PD-L1 small molecule inhibitor and application thereof in medicines | 广东东阳光药业有限公司 | 2022-10-25 | — | — | CN | claimed |
| CN-113072521-A | ROR gamma t inhibitor and application thereof in medicine | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | claimed |
| EP-3347097-B1 | SUBSTITUTED AMINOPYRIMIDINE DERIVATIVES AS MODULATORS OF THE KINASES JAK, FLT3 AND AURORA | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-02-24 | — | — | EP | claimed |
| CN-105803789-B | A kind of surface modification of aramid fiber and preparation method thereof | 深圳市新纶科技股份有限公司 | 2018-01-02 | — | — | CN | claimed |
| WO-2017178511-A1 | METHOD OF TREATMENT OF PARKINSONISM | FUNDACIÓ CENTRE DE REGULACIÓ GENÒMICA (ES) | 2017-10-19 | — | — | WO | claimed |
| EP-3231434-A1 | METHOD OF TREATMENT OF PARKINSONISM | Fundacio Centre de Regulacio Genomica (ES) | 2017-10-18 | — | — | EP | claimed |
| US-9765091-B2 | Tetrahydropyrazolo [3,4-b] azepine derivatives and their use as allosteric modulators of metabotropic glutamate receptors | ADDEX PHARMA S.A. (CH) | 2017-09-19 | — | — | US | claimed |
| US-20020016010-A1 | Synthesis of compounds and libraries of compounds | PRESIDENT AND FELLOWS OF HARVARD COLLEGE | 2002-02-07 | — | — | US | claimed |
| EP-1066295-A2 | SYNTHESIS OF COMPOUNDS AND LIBRARIES OF COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2001-01-10 | — | — | EP | claimed |
| WO-1999048897-A2 | SYNTHESIS OF COMPOUNDS AND LIBRARIES OF COMPOUNDS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1999-09-30 | — | — | WO | claimed |
| EP-0332022-B1 | Magnetic protein conjugates, process for their production and their use | BEHRINGWERKE AG (DE) | 1994-11-30 | — | — | EP | claimed |
| US-4927902-A | REACTION PRODUCT OF HYDROGEN SULFIDE OR ORGANIC DITHIOLS WITH POLYGLYCIDYL SUBSTITUTED AMINES | HENKEL CORPORATION (US) | 1990-05-22 | — | — | US | claimed |
| EP-0332022-A2 | Magnetic protein conjugates, process for their production and their use | BEHRINGWERKE Aktiengesellschaft (DE) | 1989-09-13 | — | — | EP | claimed |
| EP-0329093-A2 | Polythiols and use as epoxy resin curing agents | HENKEL CORPORATION (a Delaware corp.) (US) | 1989-08-23 | — | — | EP | claimed |
| US-4716168-A | STIMULANTS OF IMMUNE RESPONSE | NORWICH EATON PHARMACEUTICALS, INC. (US) | 1987-12-29 | — | — | US | claimed |
| EP-0187705-A2 | Imidazo(4,5-f)quinolines useful as immunomodulating agents | Norwich Eaton Pharmaceuticals, Inc. (US) | 1986-07-16 | — | — | EP | claimed |
| US-4560648-A | CONJUGATED THROUGH THIO GROUP OF B-GALACTOSIDASE | SYNTEX (U.S.A.) INC. (US) | 1985-12-24 | — | — | US | claimed |