⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL100581 | 0.90 | — | — | |
| SCHEMBL104277 | 0.88 | — | — | |
| SCHEMBL9498346 | 0.69 | — | — | |
| SCHEMBL204351 | 0.69 | — | — | |
| SCHEMBL5898285 | 0.69 | — | — | |
| SCHEMBL9499463 | 0.65 | — | — | |
| SCHEMBL8763215 | 0.61 | — | — | |
| SCHEMBL67399 | 0.60 | — | — | |
| SCHEMBL602295 | 0.60 | — | — | |
| SCHEMBL9335399 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 857 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116283946-B | 5- (N-substituted indole-5-yl) isoxazole-3-formic acid derivative and synthetic method and application thereof | 武汉工程大学 | 2024-05-07 | — | — | CN | claimed |
| CN-117886839-A | Organic semiconductor luminescent compound and application thereof | 冠能光电材料(深圳)有限责任公司 | 2024-04-16 | — | — | CN | claimed |
| CN-117886814-A | PD-1/PD-L1 small molecule inhibitor and application thereof in medicines | 广东东阳光药业股份有限公司 | 2024-04-16 | — | — | CN | claimed |
| CN-116804023-A | Organic semiconductor luminescent compound and application thereof | 冠能光电材料(深圳)有限责任公司 | 2023-09-26 | — | — | CN | claimed |
| CN-116283946-A | 5- (N-substituted indole-5-yl) isoxazole-3-formic acid derivative and synthetic method and application thereof | 武汉工程大学 | 2023-06-23 | — | — | CN | claimed |
| CN-115232109-A | PD-1/PD-L1 small molecule inhibitor and application thereof in medicines | 广东东阳光药业有限公司 | 2022-10-25 | — | — | CN | claimed |
| CN-113072521-A | ROR gamma t inhibitor and application thereof in medicine | 广东东阳光药业有限公司 | 2021-07-06 | — | — | CN | claimed |
| EP-3347097-B1 | SUBSTITUTED AMINOPYRIMIDINE DERIVATIVES AS MODULATORS OF THE KINASES JAK, FLT3 AND AURORA | SUNSHINE LAKE PHARMA CO LTD (CN) | 2021-02-24 | — | — | EP | claimed |
| US-9765091-B2 | Tetrahydropyrazolo [3,4-b] azepine derivatives and their use as allosteric modulators of metabotropic glutamate receptors | ADDEX PHARMA S.A. (CH) | 2017-09-19 | — | — | US | claimed |
| US-20170258786-A1 | RBP4 ANTAGONISTS FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION AND STARGARDT DISEASE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2017-09-14 | — | — | US | claimed |
| WO-2006093823-A1 | 2- [ ISOQUINOLIN-S - CARBONYL ) AMINO] -PROPIONIC ACID DERIVATIVES AS INHIBITORS OF FACTORS XI AND IX FOR THE TREATMENT OF THROMBOSIS | TRANSTECH PHARMA, INC. (US) | 2006-09-08 | — | — | WO | claimed |
| US-20060154924-A1 | Fungicidal mixtures based on morpholine or piperidine derivatives and oxime ether derivatives | SCHELBERGER KLAUS | 2006-07-13 | — | — | US | claimed |
| US-7026315-B1 | Fungicide mixtures which are based on derivatives of morpholine or piperidine and derivatives oxime ether | BASF AKTIENGESELLSCHAFT (DE) | 2006-04-11 | — | — | US | claimed |
| US-20050171148-A1 | Aryl and heteroaryl compounds, compositions, methods of use | TRANSTECH PHARMA, LLC | 2005-08-04 | — | — | US | claimed |
| EP-1499588-A1 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2005-01-26 | — | — | EP | claimed |
| US-20040010010-A1 | Melanocortin receptor ligands | PROCTER & GAMBLE COMPANY, THE | 2004-01-15 | — | — | US | claimed |
| US-20030236230-A1 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY | 2003-12-25 | — | — | US | claimed |
| WO-2003093234-A1 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2003-11-13 | — | — | WO | claimed |
| US-6531498-B1 | Antiallergens, etc | MERCK PATENTGESELLSCHAFT (DE) | 2003-03-11 | — | — | US | claimed |
| US-6376493-B1 | SELECTIVE INHIBITION OF PHOSPHODIESTERASE IV AND TUMOR NECROSIS FACTOR; USEFUL IN TREATING OSTEOPOROSIS, TUMORS, AUTOIMMUNE DISEASES, RHEUMATIC DISEASES, AND ASTHMA | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2002-04-23 | — | — | US | claimed |