Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | UPP1 | Q16831 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | TYMP | P19971 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15996298 | 0.86 | CYP3A4 (0.45) | MAPTCYP3A4UPP1ADRB2HTR6 | |
| SCHEMBL6044950 | 0.73 | MAPT (0.38) | MAPTCYP3A4UPP1ADRB2ALDH1A1 | |
| SCHEMBL6088155 | 0.70 | CYP3A4 (0.38) | MAPTCYP3A4UPP1ALDH1A1KDM4E | |
| 2-Methyl Gramine SCHEMBL2519973 | 0.69 | MAPT (1.00) | MAPTCYP3A4HTR6ALDH1A1KDM4E | |
| SCHEMBL28135724 | 0.66 | CYP3A4 (0.38) | MAPTCYP3A4ADRB2ALDH1A1KDM4E | |
| SCHEMBL10146022 | 0.66 | MAPK1 (0.48) | MAPTALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL14279381 | 0.63 | ALDH1A1 (0.41) | MAPTCYP3A4UPP1ADRB2ALDH1A1 | |
| SCHEMBL3199967 | 0.63 | HTR1D (0.38) | MAPTCYP3A4ALDH1A1KDM4EHPGD | |
| SCHEMBL11826128 | 0.63 | UPP1 (0.38) | MAPTCYP3A4UPP1ADRB2ALDH1A1 | |
| SCHEMBL2884631 | 0.63 | CYP3A4 (0.32) | MAPTCYP3A4UPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3124490-A1 | HIGH STABILITY POLYIONIC LIQUID SALTS | Sigma-Aldrich Co. LLC (US) | 2017-02-01 | — | — | EP | disclosed |
| EP-2114969-B1 | HIGH STABILITY POLYIONIC LIQUID SALTS | SIGMA ALDRICH CO LLC (US) | 2016-06-29 | — | — | EP | disclosed |
| US-8481722-B2 | High stability polyionic liquid salts | SIGMA-ALDRICH CO. LLC (US) | 2013-07-09 | — | — | US | disclosed |
| US-8481722-B2 | High stability polyionic liquid salts | SIGMA-ALDRICH CO. LLC (US) | 2013-07-09 | — | — | US | disclosed |
| US-20120083603-A1 | HIGH STABILITY POLYIONIC LIQUID SALTS | SIGMA-ALDRICH CO. LLC (US) | 2012-04-05 | — | — | US | disclosed |
| US-20120083603-A1 | HIGH STABILITY POLYIONIC LIQUID SALTS | SIGMA-ALDRICH CO. LLC (US) | 2012-04-05 | — | — | US | disclosed |
| US-8097721-B2 | polycationic or polyanionic molecules; use as stationary phases in gas chromatography, and as a reagent in electrospray ionization-mass spectrometry (ESI-MS); thermal stability; tris(anion) such as tris(sulfonate) or tris(cation) groups such as imidazolium, pyrrolidinium, ammonium | SIGMA-ALDRICH CO. LLC (US) | 2012-01-17 | — | — | US | disclosed |
| US-8097721-B2 | polycationic or polyanionic molecules; use as stationary phases in gas chromatography, and as a reagent in electrospray ionization-mass spectrometry (ESI-MS); thermal stability; tris(anion) such as tris(sulfonate) or tris(cation) groups such as imidazolium, pyrrolidinium, ammonium | SIGMA-ALDRICH CO. LLC (US) | 2012-01-17 | — | — | US | disclosed |
| US-20080210858-A1 | High Stability Polyionic Liquid Salts | SIGMA-ALDRICH CO. NEWCO INC. | 2008-09-04 | — | — | US | disclosed |
| US-20080210858-A1 | High Stability Polyionic Liquid Salts | SIGMA-ALDRICH CO. NEWCO INC. | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080210858-A1 | High Stability Polyionic Liquid Salts | PUF60, POLI, PARG | MAPT 1190/4885CYP3A4 4661/4885UPP1 3199/4885 |
| US-20120083603-A1 | HIGH STABILITY POLYIONIC LIQUID SALTS | PUF60, POLI, PARG | MAPT 1190/4885CYP3A4 4661/4885UPP1 3199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.