SCHEMBL2884631

SCHEMBL2884631

Cc1c(C)c(CN(C)C)c(C)c(C)c1N

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
UPP1 Q16831 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6044950 0.80 MAPT (0.38) CYP3A4MAPTUPP1
SCHEMBL14890983 0.72 ALDH1A1 (0.42) CYP3A4MAPTUPP1
SCHEMBL17482328 0.72 UPP1 (0.37) CYP3A4MAPTUPP1
SCHEMBL9815453 0.71
SCHEMBL6589823 0.70 CYP3A4 (0.36) CYP3A4MAPTUPP1
SCHEMBL11278413 0.70 ALDH1A1 (0.39) CYP3A4MAPTUPP1
SCHEMBL12629478 0.69 NOS3 (0.34)
SCHEMBL263364 0.69 POLB (0.37) CYP3A4
SCHEMBL11826128 0.68 UPP1 (0.38) CYP3A4MAPTUPP1
SCHEMBL19988140 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7670753-B2 Lithographic printing plate precursor EASTMAN KODAK COMPANY (US) 2010-03-02 US disclosed
US-20080261146-A1 Lithographic Printing Plate Precursor EASTMAN KODAK COMPANY 2008-10-23 US disclosed
EP-1782127-B1 LITHOGRAPHIC PRINTING PLATE PRECURSOR EASTMAN KODAK CO (US) 2008-04-02 EP disclosed
EP-1782127-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR EASTMAN KODAK COMPANY (US) 2007-05-09 EP disclosed
WO-2006023667-A1 LITHOGRAPHIC PRINTING PLATE PRECURSOR EASTMAN KODAK COMPANY (US) 2006-03-02 WO disclosed