SCHEMBL1005904

SCHEMBL1005904

Brc1cc(Br)c2ccc3c(Br)cc(Br)c4ccc1c2c43

nearest known ligand 0.37

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 2/20 0.33
HTT P42858 2/20 0.33
TDP1 Q9NUW8 2/20 0.33
BCL2 P10415 1/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
USP2 O75604 1/20 0.33
TP53 P04637 1/20 0.33
KMT2A Q03164 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
MAPT P10636 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CSNK2A1 P68400 1/20 0.31
HIPK2 Q9H2X6 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA6 P23280 1/20 0.30
APEX1 P27695 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29851093 0.86 HIPK2 (0.32) HSP90AA1HTTMAPTCSNK2A1HIPK2
SCHEMBL18094451 0.84 ALDH1A1 (0.35) HTTTDP1KDM4EMEN1TP53
SCHEMBL30045816 0.84 CYP1A2 (0.35) TDP1ALDH1A1
SCHEMBL2085261 0.84 CYP1A2 (0.35) TDP1ALDH1A1
SCHEMBL14302441 0.84 ALDH1A1 (0.35) TDP1KDM4EMEN1KMT2AALDH1A1
SCHEMBL25224508 0.82 TDP1 (0.47) HSP90AA1HTTTDP1KDM4EMEN1
SCHEMBL2122425 0.82 ALDH1A1 (0.52) TDP1KDM4EMEN1TP53KMT2A
SCHEMBL12331166 0.80
SCHEMBL16558503 0.80
SCHEMBL1705445 0.80 ALDH1A1 (0.36) TDP1KDM4EMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 483 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058531-A Organic compound 1,3,6, 8-tetra (m-aniline) pyrene, one-dimensional covalent organic framework, and preparation method and application thereof 中国科学院福建物质结构研究所 2025-05-30 CN claimed
US-12263465-B2 Tailoring new covalent organic framework for highly efficient iodine capture UNITED ARAB EMIRATES UNIVERSITY (AE) 2025-04-01 US claimed
CN-119708513-A Covalent organic framework and preparation method thereof 深圳大学 2025-03-28 CN claimed
CN-119455678-A Preparation method and application of double-function composite membrane material based on hollow conjugated microporous polymer microsphere loaded titanium dioxide 西北民族大学 2025-02-18 CN claimed
CN-119390951-A Imino conjugated microporous polymer with high specific surface area and high conjugation degree and preparation method and application thereof 东华大学 2025-02-07 CN claimed
US-20250033025-A1 TAILORING NEW COVALENT ORGANIC FRAMEWORK FOR HIGHLY EFFICIENT IODINE CAPTURE UNITED ARAB EMIRATES UNIVERSITY (AE) 2025-01-30 US claimed
CN-119331264-A Pyrenyl metal organic framework material suitable for low-temperature methane adsorption storage, and preparation and application thereof 浙江大学杭州国际科创中心 2025-01-21 CN claimed
CN-119318890-A Long-range conjugated organic/inorganic gas separation membrane and preparation method thereof 国能神东煤炭集团有限责任公司 2025-01-17 CN claimed
CN-119119397-A Polymer containing oxygen-sulfur bond and preparation method and application thereof 江苏科技大学 2024-12-13 CN claimed
CN-118955380-A Pyrazole organic monomer, preparation method thereof, three-dimensional MOF material and application thereof 云南大学 2024-11-15 CN claimed
CN-107674021-A Ancient cooking vessel shape tetramine pyrene and the film modified electrode of preparation method, ancient cooking vessel shape tetramine pyrene and preparation method 中国科学院化学研究所 2018-02-09 CN claimed
US-20160256905-A1 HYDROCARBON SORBENT MATERIALS JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) 2016-09-08 US claimed
CN-105632773-A Method for improving photoelectric conversion efficiency of dye-sensitized solar cell UNIV BEIJING CHEMICAL TECH 2016-06-01 CN claimed
CN-105111216-A Thiophene polycyclic organic semiconductor material synthesis based on pyrene BEIJING INST TECHNOLOGY 2015-12-02 CN claimed
US-20150207078-A1 FLUORINATED AROMATIC MATERIALS AND THEIR USE IN OPTOELECTRONICS THE UNIVERSITY OF SOUTH DAKOTA 2015-07-23 US claimed
US-20130327716-A1 HYDROCARBON SORBENT MATERIALS JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) 2013-12-12 US claimed
WO-2013042073-A1 POLYMER, METHODS OF OBTAINING THE POLYMER AND APPLICATIONS THEREOF JAWAHARLAL NEHRU CENTRE FOR ADVANCED SCIENTIFIC RESEARCH (IN) 2013-03-28 WO claimed
EP-0216204-B1 PROCESS FOR THE PREPARATION OF 1,3,6,8-TETRABROMOPYRENE HOECHST AKTIENGESELLSCHAFT (DE) 1989-04-12 EP claimed
US-4684753-A Process for preparing 1,3,6,8-tetrabromopyrene HOECHST AKTIENGESELLSCHAFT (DE) 1987-08-04 US claimed
EP-0216204-A1 Process for the preparation of 1,3,6,8-tetrabromopyrene HOECHST AKTIENGESELLSCHAFT (DE) 1987-04-01 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12263465-B2 Tailoring new covalent organic framework for highly efficient iodine capture POF1B, PIKFYVE, TPO HSP90AA1 4448/4885HTT 1805/4885TDP1 3516/4885
US-20250033025-A1 TAILORING NEW COVALENT ORGANIC FRAMEWORK FOR HIGHLY EFFICIENT IODINE CAPTURE POF1B, PIKFYVE, TPO HSP90AA1 4448/4885HTT 1805/4885TDP1 3516/4885
US-20150207078-A1 FLUORINATED AROMATIC MATERIALS AND THEIR USE IN OPTOELECTRONICS ALK, SLCO2A1, SLCO2B1 HSP90AA1 3531/4885HTT 290/4885TDP1 2659/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.