Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2918731 | 0.84 | — | — | |
| SCHEMBL17918827 | 0.78 | ADH1A (0.46) | ADH1CADH1A | |
| SCHEMBL21574233 | 0.78 | HTT (0.35) | PIK3CDKDM4ECSF1RCNR2HTT | |
| SCHEMBL10059247 | 0.75 | SLC6A1 (0.35) | ADH1CADH1AUSP2ALOX15 | |
| SCHEMBL24085856 | 0.75 | PIK3CD (0.40) | PIK3CDKDM4ECSF1RCNR2HTT | |
| SCHEMBL12909219 | 0.75 | PIK3CD (0.40) | PIK3CDKDM4ECSF1RCNR2HTT | |
| SCHEMBL18433509 | 0.73 | CNR2 (0.38) | PIK3CDKDM4ECNR2CHRM2CHRM1 | |
| SCHEMBL22519844 | 0.71 | PIK3CD (0.38) | PIK3CDKDM4ECSF1RCNR2HTT | |
| SCHEMBL18784057 | 0.71 | PIK3CD (0.38) | PIK3CDKDM4ECSF1RCNR2HTT | |
| SCHEMBL13178188 | 0.71 | PIK3CD (0.38) | PIK3CDKDM4ECSF1RHTTCHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083436-A1 | TRYPSIN-LIKE SERINE PROTEASE INHIBITORS, THEIR PREPARATION AND USE AS SELECTIVE INHIBITORS OF THE CLOTTING FACTORS IIA AND XA | THE MEDICINES COMPANY (LEIPZIG) GMBH (DE) | 2012-06-28 | — | — | WO | disclosed |