Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.63 |
| ▸ | PTPRC | P08575 | 2/20 | 0.56 |
| ▸ | TDP2 | O95551 | 1/20 | 0.53 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.51 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.51 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.51 |
| ▸ | RXRA | P19793 | 3/20 | 0.50 |
| ▸ | RXRB | P28702 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | BAD | Q92934 | 1/20 | 0.50 |
| ▸ | RXRG | P48443 | 1/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12187738 | 0.92 | PTPRC (0.61) | TTRPTPRCTDP2GRIK1GRIK2 | |
| SCHEMBL15072035 | 0.89 | PTPRC (0.74) | TTRPTPRCTDP2RXRARXRB | |
| SCHEMBL12163410 | 0.84 | TTR (0.47) | TTRPTPRCTDP2GRIK1GRIK2 | |
| SCHEMBL23453349 | 0.83 | TTR (0.57) | TTRPTPRCGRIK1GRIK2GRIK3 | |
| SCHEMBL31436145 | 0.83 | TTR (0.88) | TTRPTPRCMEN1MAPTKMT2A | |
| SCHEMBL71021 | 0.83 | TTR (0.88) | TTRPTPRCMEN1MAPTKMT2A | |
| SCHEMBL598301 | 0.83 | TTR (0.88) | TTRPTPRCMEN1MAPTKMT2A | |
| SCHEMBL10060718 | 0.81 | ALDH1A1 (0.59) | TTRPTPRCTDP2GRIK1GRIK2 | |
| SCHEMBL724251 | 0.79 | TDP2 (0.53) | TDP2GRIK1GRIK2GRIK3RXRA | |
| SCHEMBL599578 | 0.79 | TTR (0.81) | TTRPTPRCLMNAMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588921-B1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KK (JP) | 2017-11-15 | — | — | EP | disclosed |
| US-8795936-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2014-08-05 | — | — | US | disclosed |
| US-20120230727-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2012-09-13 | — | — | US | disclosed |
| WO-2012002516-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2012-01-05 | — | — | WO | disclosed |