SCHEMBL10061011

SCHEMBL10061011

COc1ccc2c(C[C@H](N)C(=O)O)cc(=O)oc2c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 7/20 0.67
▸ LCK P06239 1/20 0.67
▸ ALDH1A1 P00352 6/20 0.62
▸ HPGD P15428 4/20 0.62
▸ CYP2D6 P10635 2/20 0.60
▸ CA12 O43570 3/20 0.57
▸ CA1 P00915 3/20 0.57
▸ CA2 P00918 3/20 0.57
▸ CA9 Q16790 3/20 0.57
▸ CA3 P07451 1/20 0.57
▸ CA4 P22748 1/20 0.57
▸ CA5A P35218 1/20 0.57
▸ CA7 P43166 1/20 0.57
▸ CA14 Q9ULX7 1/20 0.57
▸ CA5B Q9Y2D0 1/20 0.57
▸ HSD17B10 Q99714 2/20 0.56
▸ LMNA P02545 1/20 0.56
▸ NPSR1 Q6W5P4 1/20 0.56
▸ CYP19A1 P11511 1/20 0.55
▸ MEN1 O00255 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14473551 1.00 KDM4E (0.67) KDM4ELCKALDH1A1HPGDCYP2D6
SCHEMBL31537502 1.00 KDM4E (0.67) KDM4ELCKALDH1A1HPGDCYP2D6
SCHEMBL5272449 1.00 KDM4E (0.67) KDM4ELCKALDH1A1HPGDCYP2D6
SCHEMBL5622778 0.94 KDM4E (0.61) KDM4ELCKALDH1A1HPGDCYP2D6
SCHEMBL5622781 0.94 KDM4E (0.61) KDM4ELCKALDH1A1HPGDCYP2D6
Trifluoroacetic Acid SCHEMBL5622459 0.93 KDM4E (0.60) KDM4ELCKALDH1A1HPGDCYP2D6
Trifluoroacetic Acid SCHEMBL6028156 0.93 KDM4E (0.60) KDM4ELCKALDH1A1HPGDCYP2D6
Trifluoroacetic Acid SCHEMBL5622457 0.93 KDM4E (0.60) KDM4ELCKALDH1A1HPGDCYP2D6
SCHEMBL17874880 0.90 KDM4E (0.64) KDM4ELCKALDH1A1HPGDCYP2D6
SCHEMBL16728147 0.90 KDM4E (0.64) KDM4ELCKALDH1A1HPGDCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240197896-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY FELDAN BIO INC. (CA) 2024-06-20 — — US claimed
CN-117750978-A Synthetic peptide shuttle bioconjugates for intracellular cargo delivery 费尔丹生物公司 2024-03-22 — — CN claimed
EP-4313159-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY Feldan Bio Inc. (CA) 2024-02-07 — — EP claimed
US-20230399661-A1 SHUTTLE AGENT PEPTIDES OF MINIMAL LENGTH AND VARIANTS THEREOF ADAPTED FOR TRANSDUCTION OF CAS9-RNP AND OTHER NUCLEOPROTEIN CARGOS FELDAN BIO INC. (CA) 2023-12-14 — — US claimed
US-20230383291-A1 PEPTIDE-BASED TRANSDUCTION OF NON-ANIONIC POLYNUCLEOTIDE ANALOGS FOR GENE EXPRESSION MODULATION FELDAN BIO INC. (CA) 2023-11-30 — — US claimed
EP-4232590-A1 SHUTTLE AGENT PEPTIDES OF MINIMAL LENGTH AND VARIANTS THEREOF ADAPTED FOR TRANSDUCTION OF CAS9-RNP AND OTHER NUCLEOPROTEIN CARGOS Feldan Bio Inc. (CA) 2023-08-30 — — EP claimed
EP-4229207-A1 PEPTIDE-BASED TRANSDUCTION OF NON-ANIONIC POLYNUCLEOTIDE ANALOGS FOR GENE EXPRESSION MODULATION Feldan Bio Inc. (CA) 2023-08-23 — — EP claimed
CN-116615205-A Peptide-based transduction of non-anionic polynucleotide analogs for modulation of gene expression 费尔丹生物公司 2023-08-18 — — CN claimed
CN-116615227-A Minimum length shuttle peptide suitable for transduction of Cas9-RNP and other nucleoprotein loads and variants thereof 费尔丹生物公司 2023-08-18 — — CN claimed
WO-2022082315-A1 SHUTTLE AGENT PEPTIDES OF MINIMAL LENGH AND VARIANTS THEREOF ADAPTED FOR TRANSDUCTION OF CAS9-RNP AND OTHER NUCLEOPROTEIN CARGOS FELDAN BIO INC. (CA) 2022-04-28 — — WO claimed
WO-2022077121-A1 PEPTIDE-BASED TRANSDUCTION OF NON-ANIONIC POLYNUCLEOTIDE ANALOGS FOR GENE EXPRESSION MODULATION FELDAN BIO INC. (CA) 2022-04-21 — — WO claimed
EP-3956348-A1 PEPTIDE-BASED NON-PROTEINACEOUS CARGO DELIVERY Feldan Bio Inc. (CA) 2022-02-23 — — EP claimed
CN-114008210-A Peptide-based non-protein cargo delivery 费尔丹生物公司 2022-02-01 — — CN claimed
WO-2020210916-A1 PEPTIDE-BASED NON-PROTEINACEOUS CARGO DELIVERY FELDAN BIO INC. (CA) 2020-10-22 — — WO claimed
US-12018057-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases JANSSEN BIOTECH, INC. (US) 2024-06-25 — — US disclosed
US-12018057-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases JANSSEN BIOTECH, INC. (US) 2024-06-25 — — US disclosed
US-20240197896-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY FELDAN BIO INC. (CA) 2024-06-20 — — US disclosed
US-8278045-B2 Methods for the detection, analysis and isolation of nascent proteins AMBERGEN, INC. (US) 2012-10-02 — — US disclosed
US-8148062-B2 Detection of disease related genes AMBERGEN, INC. (US) 2012-04-03 — — US disclosed
US-20070148680-A1 Detection of disease related genes THE TRUSTEES OF BOSTON UNIVERSITY 2007-06-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197896-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY SCAMP2, SLC7A1, NUMA1 KDM4E 4852/4885LCK 3166/4885ALDH1A1 4747/4885
US-12018057-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases IL23R, IL1RN, VIP KDM4E 4705/4885LCK 1384/4885ALDH1A1 4574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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