Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.52 |
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NT5E | P21589 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 7/20 | 0.45 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10062035 | 0.85 | SLC10A1 (0.54) | SLC10A1GPBAR1LMNANT5ESMN1; SMN2 | |
| SCHEMBL5451153 | 0.84 | SLC10A1 (0.45) | SLC10A1GPBAR1LMNANT5ESMN1; SMN2 | |
| SCHEMBL13908732 | 0.82 | GPBAR1 (0.52) | SLC10A1GPBAR1LMNANT5ESMN1; SMN2 | |
| SCHEMBL17794078 | 0.82 | GPBAR1 (0.52) | SLC10A1GPBAR1LMNANT5ESMN1; SMN2 | |
| SCHEMBL10061314 | 0.82 | GPBAR1 (0.52) | SLC10A1GPBAR1LMNANT5ESMN1; SMN2 | |
| SCHEMBL13908800 | 0.82 | GPBAR1 (0.52) | SLC10A1GPBAR1LMNANT5ESMN1; SMN2 | |
| Dihydrobetulonic Acid SCHEMBL14414141 | 0.80 | GPBAR1 (0.71) | GPBAR1LMNANT5ESMN1; SMN2PRKCD | |
| Dihydrobetulonic Acid SCHEMBL13908784 | 0.80 | GPBAR1 (0.71) | GPBAR1LMNANT5ESMN1; SMN2PRKCD | |
| Dihydrobetulonic Acid SCHEMBL10061167 | 0.80 | GPBAR1 (0.71) | GPBAR1LMNANT5ESMN1; SMN2PRKCD | |
| Dihydrobetulonic Acid SCHEMBL3276418 | 0.80 | GPBAR1 (0.71) | GPBAR1LMNANT5ESMN1; SMN2PRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088152-B1 | N'-{N-[3-OXO-LUPEN-28-OYL]-9-AMINONONANOYL}-3-AMINO-3-PHENYLPROPEONIC ACID AND THE PHARMACEUTICALLY ACCEPTABLE DERIVATIVES THEREOF, A METHOD FOR THE PRODUCTION AND THE USE THEREOF IN THE FORM OF A MEDICINAL AGENT | INST NEFTEKHIMII I KATALIZA ROSSIISKOI AKADEMII NAUK (RU) | 2012-02-01 | — | — | EP | disclosed |