Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 19/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | NT5E | P21589 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dihydrobetulonic Acid SCHEMBL3276418 | 1.00 | GPBAR1 (0.71) | GPBAR1LMNANT5ESMN1; SMN2PRKCD | |
| Dihydrobetulonic Acid SCHEMBL13908784 | 1.00 | GPBAR1 (0.71) | GPBAR1LMNANT5ESMN1; SMN2PRKCD | |
| Dihydrobetulonic Acid SCHEMBL14414141 | 1.00 | GPBAR1 (0.71) | GPBAR1LMNANT5ESMN1; SMN2PRKCD | |
| SCHEMBL10061168 | 0.91 | GPBAR1 (0.59) | GPBAR1LMNANT5ESMN1; SMN2PRKCD | |
| SCHEMBL16511700 | 0.91 | GPBAR1 (0.59) | GPBAR1LMNANT5ESMN1; SMN2PRKCD | |
| SCHEMBL13956965 | 0.90 | GPBAR1 (0.69) | GPBAR1LMNANT5ESMN1; SMN2PRKCD | |
| Methyl Dihydrobetulonate SCHEMBL13747683 | 0.89 | GPBAR1 (0.58) | GPBAR1LMNANT5ESMN1; SMN2PRKCD | |
| SCHEMBL13301977 | 0.89 | GPBAR1 (0.65) | GPBAR1LMNANT5ESMN1; SMN2PRKCD | |
| SCHEMBL9891261 | 0.89 | GPBAR1 (0.57) | GPBAR1LMNANT5ESMN1; SMN2PRKCD | |
| SCHEMBL14134447 | 0.89 | GPBAR1 (0.65) | GPBAR1LMNANT5ESMN1; SMN2PRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088152-B1 | N'-{N-[3-OXO-LUPEN-28-OYL]-9-AMINONONANOYL}-3-AMINO-3-PHENYLPROPEONIC ACID AND THE PHARMACEUTICALLY ACCEPTABLE DERIVATIVES THEREOF, A METHOD FOR THE PRODUCTION AND THE USE THEREOF IN THE FORM OF A MEDICINAL AGENT | INST NEFTEKHIMII I KATALIZA ROSSIISKOI AKADEMII NAUK (RU) | 2012-02-01 | — | — | EP | disclosed |
| US-8022055-B2 | Betulinic acid derivatives | DABUR PHARMA LIMITED (IN) | 2011-09-20 | — | — | US | disclosed |
| US-8022055-B2 | Betulinic acid derivatives | DABUR PHARMA LIMITED (IN) | 2011-09-20 | — | — | US | disclosed |
| US-20100273801-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | Valition teknillinen tutikimuskeskus (FI) | 2010-10-28 | — | — | US | disclosed |
| US-20100273801-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | Valition teknillinen tutikimuskeskus (FI) | 2010-10-28 | — | — | US | disclosed |
| US-20100196290-A1 | COMPOSITIONS COMPRISING BETULONIC ACID | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2010-08-05 | — | — | US | disclosed |
| US-20100196290-A1 | COMPOSITIONS COMPRISING BETULONIC ACID | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2010-08-05 | — | — | US | disclosed |
| US-20100190795-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIPROTOZOAL AGENTS | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2010-07-29 | — | — | US | disclosed |
| US-20100087539-A1 | N'--3-AMINO-3-PHENYLPROPEONIC ACID AND THE PHARMACEUTICALLY ACCEPTABLE DERIVATIVES THEREOF, A METHOD FOR THE PRODUCTION AND THE USE THEREOF IN THE FORM OF A MEDICINAL AGENT | INSTITUT NEFTEKHIMII I KATALIZA ROSSIISKOI AKADEMII NAUK (RU) | 2010-04-08 | — | — | US | disclosed |
| US-20100087539-A1 | N'--3-AMINO-3-PHENYLPROPEONIC ACID AND THE PHARMACEUTICALLY ACCEPTABLE DERIVATIVES THEREOF, A METHOD FOR THE PRODUCTION AND THE USE THEREOF IN THE FORM OF A MEDICINAL AGENT | INSTITUT NEFTEKHIMII I KATALIZA ROSSIISKOI AKADEMII NAUK (RU) | 2010-04-08 | — | — | US | disclosed |
| EP-2088152-A1 | N'-{N-[3-OXO-LUPEN-28-OYL]-9-AMINONONANOYL}-3-AMINO-3-PHENYLPROPEONIC ACID AND THE PHARMACEUTICALLY ACCEPTABLE DERIVATIVES THEREOF, A METHOD FOR THE PRODUCTION AND THE USE THEREOF IN THE FORM OF A MEDICINAL AGENT | Institut Neftekhimii I Kataliza Rossiiskoi Akademii Nauk (RU) | 2009-08-12 | — | — | EP | disclosed |
| US-20080293682-A1 | Novel Betulinic Acid Derivatives | DABUR PHARMA LIMITED (IN) | 2008-11-27 | — | — | US | disclosed |
| US-20080293682-A1 | Novel Betulinic Acid Derivatives | DABUR PHARMA LIMITED (IN) | 2008-11-27 | — | — | US | disclosed |
| WO-2007141390-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIVIRAL AGENTS | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007141389-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2007-12-13 | — | — | WO | disclosed |
| WO-2007141391-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIPROTOZOAL AGENTS | VALTION TEKNILLINEN TUTKIMUSKESKUS (FI) | 2007-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080293682-A1 | Novel Betulinic Acid Derivatives | BET1, PGGT1B, RABGGTB | GPBAR1 84/4885LMNA 1944/4885NT5E 2619/4885 |
| US-20100087539-A1 | N'--3-AMINO-3-PHENYLPROPEONIC ACID AND THE PHARMACEUTICALLY ACCEPTABLE DERIVATIVES THEREOF, A METHOD FOR THE PRODUCTION AND THE USE THEREOF IN THE FORM OF A MEDICINAL AGENT | GART, DNPEP, IL4I1 | GPBAR1 516/4885LMNA 2743/4885NT5E 551/4885 |
| US-20100196290-A1 | COMPOSITIONS COMPRISING BETULONIC ACID | BET1, PGGT1B, RABGGTB | GPBAR1 764/4885LMNA 3692/4885NT5E 1111/4885 |
| US-20100273801-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIBACTERIAL AGENTS | BET1, CUTA, BECN1 | GPBAR1 1652/4885LMNA 3874/4885NT5E 1606/4885 |
| US-20100190795-A1 | BETULIN DERIVED COMPOUNDS USEFUL AS ANTIPROTOZOAL AGENTS | BET1, BECN1, PGGT1B | GPBAR1 1716/4885LMNA 990/4885NT5E 2484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.