Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Meglumine SCHEMBL14126374 | 0.83 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| Meglumine SCHEMBL18270062 | 0.83 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| Meglumine SCHEMBL22562873 | 0.83 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| Meglumine SCHEMBL23363691 | 0.83 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| Meglumine SCHEMBL724392 | 0.83 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| Meglumine SCHEMBL23106596 | 0.83 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| Meglumine SCHEMBL22641548 | 0.83 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| Meglumine SCHEMBL23363692 | 0.83 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| Meglumine SCHEMBL20836266 | 0.83 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 | |
| Meglumine SCHEMBL12195402 | 0.83 | KDM4E (1.00) | KDM4ELMNAL3MBTL1TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2406225-B1 | ADDITION SALTS OF AMINES CONTAINING HYDROXYL AND/OR CARBOXYLIC GROUPS WITH AMINO NICOTINIC ACID DERIVATIVES AS DHODH INHIBITORS | ALMIRALL SA (ES) | 2013-06-26 | — | — | EP | disclosed |
| US-20120014918-A1 | ADDITION SALTS OF AMINES CONTAINING HYDROXYL AND/OR CARBOXYLIC GROUPS WITH AMINO NICOTINIC ACID DERIVATIVES AS DHODH INHIBITORS | ALMIRALL, S.A. (ES) | 2012-01-19 | — | — | US | disclosed |
| US-20120014918-A1 | ADDITION SALTS OF AMINES CONTAINING HYDROXYL AND/OR CARBOXYLIC GROUPS WITH AMINO NICOTINIC ACID DERIVATIVES AS DHODH INHIBITORS | ALMIRALL, S.A. (ES) | 2012-01-19 | — | — | US | disclosed |
| WO-2010102826-A1 | ADDITION SALTS OF AMINES CONTAINING HYDROXYL AND/OR CARBOXYLIC GROUPS WITH AMINO NICOTINIC ACID DERIVATIVES AS DHODH INHIBITORS | ALMIRALL, S.A. (ES) | 2010-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120014918-A1 | ADDITION SALTS OF AMINES CONTAINING HYDROXYL AND/OR CARBOXYLIC GROUPS WITH AMINO NICOTINIC ACID DERIVATIVES AS DHODH INHIBITORS | DHODH, DAO, ADH1B | KDM4E 3178/4885LMNA 3480/4885L3MBTL1 4807/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.