Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOS | P01100 | 1/20 | 0.77 |
| ▸ | JUN | P05412 | 1/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.66 |
| ▸ | CYP1A1 | P04798 | 5/20 | 0.65 |
| ▸ | CYP1B1 | Q16678 | 5/20 | 0.65 |
| ▸ | GSK3B | P49841 | 3/20 | 0.55 |
| ▸ | BACE1 | P56817 | 3/20 | 0.55 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | P4HB | P07237 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL610560 | 0.92 | CYP1A2 (0.77) | FOSJUNCYP1A2CYP1A1CYP1B1 | |
| SCHEMBL20586571 | 0.92 | CYP1A2 (0.77) | FOSJUNCYP1A2CYP1A1CYP1B1 | |
| SCHEMBL610559 | 0.92 | CYP1A2 (0.77) | FOSJUNCYP1A2CYP1A1CYP1B1 | |
| SCHEMBL11999777 | 0.89 | CYP1A2 (0.83) | FOSJUNCYP1A2CYP1A1CYP1B1 | |
| SCHEMBL608506 | 0.87 | FOS (1.00) | FOSJUNCYP1A2CYP1B1GSK3B | |
| SCHEMBL4442364 | 0.87 | FOS (1.00) | FOSJUNCYP1A2CYP1B1GSK3B | |
| SCHEMBL15290855 | 0.81 | FOS (0.87) | FOSJUNGSK3BBACE1TLR9 | |
| SCHEMBL8781291 | 0.81 | CYP1A2 (1.00) | JUNCYP1A2CYP1A1CYP1B1HDAC3 | |
| SCHEMBL8781296 | 0.81 | CYP1A2 (1.00) | JUNCYP1A2CYP1A1CYP1B1HDAC3 | |
| SCHEMBL31258594 | 0.81 | CYP1A2 (1.00) | JUNCYP1A2CYP1A1CYP1B1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-02-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | L1CAM, LY96, GMFG | FOS 4116/4885JUN 4222/4885CYP1A2 4526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.