Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOS | P01100 | 2/20 | 1.00 |
| ▸ | JUN | P05412 | 2/20 | 1.00 |
| ▸ | GSK3B | P49841 | 8/20 | 0.70 |
| ▸ | BACE1 | P56817 | 8/20 | 0.70 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | F3 | P13726 | 2/20 | 0.50 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4442364 | 1.00 | FOS (1.00) | FOSJUNGSK3BBACE1TLR9 | |
| SCHEMBL15290855 | 0.93 | FOS (0.87) | FOSJUNGSK3BBACE1TLR9 | |
| SCHEMBL10061357 | 0.87 | FOS (0.77) | FOSJUNGSK3BBACE1TLR9 | |
| SCHEMBL5598705 | 0.86 | JUN (0.74) | FOSJUNMAPTALDH1A1CYP3A4 | |
| SCHEMBL5598702 | 0.86 | JUN (0.74) | FOSJUNMAPTALDH1A1CYP3A4 | |
| SCHEMBL9162036 | 0.82 | MAPT (0.76) | FOSJUNMAPTALDH1A1CYP3A4 | |
| SCHEMBL11999791 | 0.82 | MAPT (0.76) | FOSJUNMAPTALDH1A1CYP3A4 | |
| SCHEMBL609968 | 0.82 | GSK3B (1.00) | FOSJUNGSK3BBACE1TLR9 | |
| SCHEMBL609967 | 0.82 | GSK3B (1.00) | FOSJUNGSK3BBACE1TLR9 | |
| SCHEMBL608387 | 0.82 | MAPT (0.75) | FOSJUNGSK3BBACE1TLR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) | 2012-02-16 | — | — | US | disclosed |
| US-20090263492-A1 | Diagnostic Methods and Genetic Markers for Alzheimer Disease | HUMAN BIOMOLECULAR RESEARCH INSTITUTE | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090263492-A1 | Diagnostic Methods and Genetic Markers for Alzheimer Disease | CHAT, SLC18A3, GAP43 | FOS 4099/4885JUN 4432/4885GSK3B 2770/4885 |
| US-20120040976-A1 | SMALL MOLECULE IMMUNOMODULATORS FOR ALZHEIMER'S DISEASE | L1CAM, LY96, GMFG | FOS 4116/4885JUN 4222/4885GSK3B 3394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.