SCHEMBL1006178

SCHEMBL1006178

NCCCCC(NC(N)=O)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.64
GSR P00390 1/20 0.50
SLC6A5 Q9Y345 1/20 0.49
RNPEP Q9H4A4 1/20 0.48
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CPB2 Q96IY4 10/20 0.45
MMP2 P08253 1/20 0.44
MMP9 P14780 1/20 0.44
GNPAT O15228 1/20 0.42
SLC15A2 Q16348 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5497824 1.00 FOLH1 (0.64) FOLH1GSRSLC6A5RNPEPCA1
SCHEMBL1006179 1.00 FOLH1 (0.64) FOLH1GSRSLC6A5RNPEPCA1
SCHEMBL3832821 0.94 FOLH1 (0.56) FOLH1GSRSLC6A5RNPEPCA1
SCHEMBL20395062 0.94 FOLH1 (0.56) FOLH1GSRSLC6A5RNPEPCA1
SCHEMBL3832820 0.94 FOLH1 (0.56) FOLH1GSRSLC6A5RNPEPCA1
SCHEMBL28210617 0.91 FOLH1 (0.55) FOLH1GSRSLC6A5RNPEPCA1
SCHEMBL12461743 0.87 GNPAT (0.52) FOLH1GNPAT
SCHEMBL43995 0.86 FOLH1 (0.66) FOLH1GSRSLC6A5RNPEPCA1
SCHEMBL12572609 0.86 FOLH1 (0.83) FOLH1GSRSLC6A5RNPEPCPB2
SCHEMBL43996 0.86 FOLH1 (0.66) FOLH1GSRSLC6A5RNPEPCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200095275-A1 SITE-SELECTIVE FUNCTIONALIZATION OF PROTEINS USING TRACELESS AFFINITY LABELS KRANTZ ALEXANDER (US) 2020-03-26 US claimed
EP-3506999-A1 OPEN-PORE MEMBRANE HAVING AN INNER SPACE-SPANNING POLYMERIC STRUCTURAL NETWORK FOR ELECTROPHORETIC MATERIAL-SELECTIVE SEPARATION AND METHODS FOR PRODUCING AND USING SAME Drei Lilien PVG GmbH & Co. KG (DE) 2019-07-10 EP claimed
WO-2018042060-A1 OPEN-PORE MEMBRANE HAVING AN INNER SPACE-SPANNING POLYMERIC STRUCTURAL NETWORK FOR ELECTROPHORETIC MATERIAL-SELECTIVE SEPARATION AND METHODS FOR PRODUCING AND USING SAME DREI LILIEN PVG GMBH & CO. KG (DE) 2018-03-08 WO claimed
US-20110201947-A1 OXIDIZED PARAOXONASE 1 AND PARAOXONASE 1/HDL PARTICLE NUMBER RATIO AS RISK MARKERS FOR CARDIOVASCULAR DISEASE THE CLEVELAND CLINIC FOUNDATION (US) 2011-08-18 US claimed
EP-2268305-A2 OXIDIZED PARAOXONASE 1 AND PARAOXONASE 1/HDL PARTICLE NUMBER RATIO AS RISK MARKERS FOR CARDIOVASCULAR DISEASE The Cleveland Clinic Foundation (US) 2011-01-05 EP claimed
WO-2009114875-A2 OXIDIZED PARAOXONASE 1 AND PARAOXONASE 1/HDL PARTICLE NUMBER RATIO AS RISK MARKERS FOR CARDIOVASCULAR DISEASE THE CLEVELAND CLINIC FOUNDATION (US) 2009-09-17 WO claimed
CN-1946416-A Tissue protective cytokines for the protection, restoration, and enhancement of responsive cells, tissues and organs with an extended therapeutic window KENNETH S WARREN INST INC (US) 2007-04-11 CN claimed
CN-1897960-A Tissue protective cytokines for protection, restoration, and enhancement of responsive cells, tissues and organs with extended therapeutic window KENNETH S WARREN INST INC (US) 2007-01-17 CN claimed
US-20240301469-A1 MODIFYING, SEPARATING AND DETECTING PROTEOFORMS NAUTILUS SUBSIDIARY, INC. 2024-09-12 US disclosed
WO-2024177827-A1 MODIFYING, SEPARATING AND DETECTING PROTEOFORMS NAUTILUS SUBSIDIARY, INC. (US) 2024-08-29 WO disclosed
CN-113759113-A Urine protein marker for diagnosing medulloblastoma and application thereof 首都医科大学附属北京天坛医院 2021-12-07 CN disclosed
EP-3897703-A2 SERUM FREE INTRACELLULAR PATHOGEN VACCINE Intervet International B.V. (NL) 2021-10-27 EP disclosed
WO-2021049330-A1 PROCESSING LIQUID, PROCESSING METHOD 富士フイルム株式会社 2021-03-18 WO disclosed
WO-2020127941-A2 SERUM FREE INTRACELLULAR PATHOGEN VACCINE INTERVET INTERNATIONAL B.V. (NL) 2020-06-25 WO disclosed
EP-0973801-B1 GnRH ANTAGONISTS FERRING BV (NL) 2002-12-18 EP disclosed
US-6214798-B1 POLYPEPTIDES FERRING BV (NL) 2001-04-10 US disclosed
EP-1003774-A1 GnRH ANTAGONISTS BEING MODIFIED IN POSITIONS 5 AND 6 FERRING B.V. (NL) 2000-05-31 EP disclosed
EP-0973801-A1 GnRH ANTAGONISTS FERRING B.V. (NL) 2000-01-26 EP disclosed
WO-1998046634-A1 GnRH ANTAGONISTS BEING MODIFIED IN POSITIONS 5 AND 6 FERRING B.V. (NL) 1998-10-22 WO disclosed
WO-1998046635-A1 GnRH ANTAGONISTS FERRING BV (NL) 1998-10-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200095275-A1 SITE-SELECTIVE FUNCTIONALIZATION OF PROTEINS USING TRACELESS AFFINITY LABELS MYCBP, FABP3, STUB1 FOLH1 1058/4885GSR 3664/4885SLC6A5 3349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.