SCHEMBL43996

SCHEMBL43996

NCCCC[C@H](NC(=O)O)C(=O)O

nearest known ligand 0.66

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.66
GSR P00390 1/20 0.52
SLC6A5 Q9Y345 1/20 0.50
RNPEP Q9H4A4 1/20 0.50
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CPB2 Q96IY4 11/20 0.46
MMP2 P08253 1/20 0.45
MMP9 P14780 1/20 0.45
GNPAT O15228 1/20 0.43
SLC15A2 Q16348 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43995 1.00 FOLH1 (0.66) FOLH1GSRSLC6A5RNPEPCA1
SCHEMBL9875634 1.00 FOLH1 (0.66) FOLH1GSRSLC6A5RNPEPCA1
Pyrrole SCHEMBL28847693 0.88 FOLH1 (0.54) FOLH1GSRSLC6A5RNPEPCA1
SCHEMBL24141430 0.88 FOLH1 (0.54) FOLH1GSRSLC6A5RNPEPCA1
SCHEMBL12572609 0.88 FOLH1 (0.83) FOLH1GSRSLC6A5RNPEPCPB2
SCHEMBL1006179 0.86 FOLH1 (0.64) FOLH1GSRSLC6A5RNPEPCA1
SCHEMBL1006178 0.86 FOLH1 (0.64) FOLH1GSRSLC6A5RNPEPCA1
SCHEMBL5497824 0.86 FOLH1 (0.64) FOLH1GSRSLC6A5RNPEPCA1
SCHEMBL30109129 0.86 FOLH1 (0.50) FOLH1GSRSLC6A5RNPEPCA1
SCHEMBL20530 0.84 FOLH1 (0.62) FOLH1GSRSLC6A5RNPEPCA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116376947-A Method suitable for screening bacterial strain with high yield of non-protein amino acid 北京理工大学 2023-07-04 CN claimed
US-20210138117-A1 COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2021-05-13 US claimed
US-10874766-B2 Compounds and matrices for use in bone growth and repair HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2020-12-29 US claimed
US-9474292-B1 Nutritional powder including brewer's yeast, aronia extract, and cranberry extract for animals EvoSci Biotech LLC (US) 2016-10-25 US claimed
US-20160038641-A1 COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2016-02-11 US claimed
EP-1858352-B1 A COMPOSITION COMPRISING A POWDER CONTAINING MICROENCAPSULATED POLYUNSATURATED LONG-CHAIN ESTERIFIED FATTY ACIDS DISTRIBUTED IN AN EFFERVESCENT BASE DELANTE HEALTH AS (NO) 2013-06-05 EP claimed
US-20080279935-A1 Composition Comprising a Powder Containing Microencapsulated Polyunsaturated Long-Chain Esterified Fatty Acids Distributed in an Effervescent Base SWG INVEST AS (NO) 2008-11-13 US claimed
EP-1858352-A1 A COMPOSITION COMPRISING A POWDER CONTAINING MICROENCAPSULATED POLYUNSATURATED LONG-CHAIN ESTERIFIED FATTY ACIDS DISTRIBUTED IN AN EFFERVESCENT BASE Core Competence Sweden AB (SE) 2007-11-28 EP claimed
WO-2006088418-A1 A COMPOSITION COMPRISING A POWDER CONTAINING MICROENCAPSULATED POLYUNSATURATED LONG-CHAIN ESTERIFIED FATTY ACIDS DISTRIBUTED IN AN EFFERVESCENT BASE CORE COMPETENCE SWEDEN AB (SE) 2006-08-24 WO claimed
US-6811793-B2 TABLET THAT INCLUDES STEVIA, WATER SOLUBLE BINDER, WATER SOLUBLE LUBRICANT, ACTIVE AGENT, AND EFFERVESCENT AGENT. AMERILAB TECHNOLOGIES, INC. 2004-11-02 US claimed
US-20030170301-A1 Effervescent composition including stevia AMERILAB TECHNOLOGIES, INC. 2003-09-11 US claimed
EP-3445343-B1 COMPOSITION AND METHOD FOR PRETREATING CANCER VALCURIA AB (SE) 2026-02-25 EP disclosed
EP-4114865-B1 PROTEASE-PROCESSED MOLECULES SANOFI SA (FR) 2026-01-28 EP disclosed
US-20250302915-A1 METHODS AND COMPOSITIONS FOR TREATMENT OF CARTILAGE DAMAGE AND ARTHRITIS NOVARTIS AG (CH) 2025-10-02 US disclosed
US-20250171512-A1 FGF21 VARIANTS SANOFI SA (FR) 2025-05-29 US disclosed
US-5480652-A HAVING IMPROVED STABILITY LABORATOIRES UPSA (FR) 1996-01-02 US disclosed
EP-0673245-A1 EFFERVESCENT PHARMACEUTICAL COMPOSITION CONTAINING IBUPROFEN AND METHOD FOR PREPARING SAME. UNION PHARMA SCIENT APPL (FR) 1995-09-27 EP disclosed
US-5437874-A Water soluble salt or complex of acetylsalicylic acid with metoclopramide or salt, stabilized with hydrophilic polymer LABORATOIRES UPSA (FR) 1995-08-01 US disclosed
WO-1995014462-A1 NOVEL PHARMACEUTICAL COMPOSITION FOR THE PREPARATION OF A STABLE POWDER CONTAINING AN ACTIVE PRINCIPLE COMPRISING AN ASSOCIATION OF ACETYLSALICYLIC ACID AND METOCLOPRAMIDE LABORATOIRES UPSA (FR) 1995-06-01 WO disclosed
WO-1994013279-A1 EFFERVESCENT PHARMACEUTICAL COMPOSITION CONTAINING IBUPROFEN AND METHOD FOR PREPARING SAME LABORATOIRES UPSA (FR) 1994-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10874766-B2 Compounds and matrices for use in bone growth and repair BMP2, BMP4, BMP6 FOLH1 2457/4885GSR 4119/4885SLC6A5 3389/4885
US-20210138117-A1 COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR BMP2, BMP4, BMP6 FOLH1 2115/4885GSR 3778/4885SLC6A5 3212/4885
US-20160038641-A1 COMPOUNDS AND MATRICES FOR USE IN BONE GROWTH AND REPAIR BMP2, BMP4, BMP6 FOLH1 2676/4885GSR 4244/4885SLC6A5 3856/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.