Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | CCR6 | P51684 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29795053 | 0.78 | MAOA (0.41) | MAOBMAOAALOX15TDP1ACHE | |
| SCHEMBL9722584 | 0.78 | MAOA (0.41) | MAOBMAOAALOX15TDP1ACHE | |
| SCHEMBL5177685 | 0.76 | MAOA (0.39) | MAOBMAOAALOX15TDP1ACHE | |
| SCHEMBL30874263 | 0.75 | MAOA (0.42) | MAOBMAOAALOX15TDP1ACHE | |
| SCHEMBL14528318 | 0.73 | TOP2A (0.51) | MAOBMAOAACHECYP19A1MEN1 | |
| Propylene Carbonate SCHEMBL29276507 | 0.72 | MAOA (0.36) | MAOBMAOAALOX15TDP1ACHE | |
| SCHEMBL11146243 | 0.71 | NSD2 (0.32) | CYP19A1MEN1POLBKMT2APKM | |
| Propene SCHEMBL29022547 | 0.71 | MAOA (0.35) | MAOBMAOAALOX15TDP1ACHE | |
| SCHEMBL2885573 | 0.71 | MEN1 (0.33) | MEN1KMT2A | |
| Phthalic Anhydride SCHEMBL3794795 | 0.70 | TDP1 (0.64) | ALOX15TDP1ACHEMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383540-B2 | Catalyst composition with halo-malonate internal electron donor and polymer from same | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-02-26 | — | — | US | disclosed |
| US-20120157296-A1 | Catalyst Composition with Halo-Malonate Internal Electron Donor and Polymer From Same | W. R. GRACE & CO.-CONN. | 2012-06-21 | — | — | US | disclosed |