SCHEMBL30874263

SCHEMBL30874263

CC1CCOC(=O)c2ccccc2C(=O)OCC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.42
MAOB P27338 1/20 0.42
ALOX15 P16050 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
ACHE P22303 3/20 0.38
TSHR P16473 3/20 0.38
MEN1 O00255 1/20 0.37
POLB P06746 1/20 0.37
KMT2A Q03164 1/20 0.37
PKM P14618 1/20 0.36
ALDH1A1 P00352 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 1/20 0.35
CASP3 P42574 1/20 0.35
HTT P42858 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35
SENP6 Q9GZR1 1/20 0.35
KDM4E B2RXH2 2/20 0.35
HPGD P15428 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23855448 0.81 HRH3 (0.33) MAOAMAOBACHETSHRALDH1A1
SCHEMBL3733365 0.79 ALOX15 (0.55) MAOAMAOBALOX15TDP1TSHR
SCHEMBL1434255 0.77 ALOX15 (0.52) MAOAMAOBALOX15TDP1TSHR
Hydrochloric Acid SCHEMBL23174308 0.77 ALOX15 (0.52) MAOAMAOBALOX15TDP1TSHR
SCHEMBL30874264 0.76 ALDH1A1 (0.36) TSHRALDH1A1SMN1; SMN2LMNAHPGD
SCHEMBL30792534 0.76 PRKCA (0.38) MAOAMAOBALOX15TDP1ACHE
SCHEMBL10061833 0.75 MAOB (0.42) MAOAMAOBALOX15TDP1ACHE
SCHEMBL24434352 0.75 MAOA (0.50) MAOAMAOBALOX15TDP1TSHR
SCHEMBL5709796 0.75 MAOA (0.50) MAOAMAOBALOX15TDP1TSHR
SCHEMBL30413722 0.75 MAOA (0.50) MAOAMAOBALOX15TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4321552-A1 CARBONATE GROUP-CONTAINING POLYOL, POLYURETHANE RESIN COMPOSITION, ARTIFICIAL LEATHER, AND LEATHER-LIKE SHEET Asahi Kasei Kabushiki Kaisha (JP) 2024-02-14 EP disclosed