Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.73 |
| ▸ | LMNA | P02545 | 5/20 | 0.73 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 8/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.68 |
| ▸ | LY96 | Q9Y6Y9 | 2/20 | 0.68 |
| ▸ | ATM | Q13315 | 2/20 | 0.68 |
| ▸ | XBP1 | P17861 | 2/20 | 0.68 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.68 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 5/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.66 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31432815 | 0.83 | MAPT (0.74) | SMN1; SMN2LMNAMAPTALDH1A1NPC1 | |
| SCHEMBL22823103 | 0.82 | SMN1; SMN2 (0.76) | SMN1; SMN2LMNAHSD17B3MAPTALDH1A1 | |
| SCHEMBL17899519 | 0.82 | HSD17B3 (1.00) | SMN1; SMN2LMNAHSD17B3MAPTALDH1A1 | |
| SCHEMBL10062876 | 0.81 | MAPT (1.00) | SMN1; SMN2LMNAHSD17B3MAPTALDH1A1 | |
| SCHEMBL11610072 | 0.81 | MAPT (1.00) | SMN1; SMN2LMNAHSD17B3MAPTALDH1A1 | |
| SCHEMBL11610067 | 0.81 | MAPT (1.00) | SMN1; SMN2LMNAHSD17B3MAPTALDH1A1 | |
| SCHEMBL17899502 | 0.79 | MEN1 (1.00) | SMN1; SMN2LMNAHSD17B3MAPTALDH1A1 | |
| SCHEMBL17899559 | 0.79 | LY96 (1.00) | SMN1; SMN2LMNAHSD17B3MAPTALDH1A1 | |
| SCHEMBL10063288 | 0.79 | KMT2A (0.76) | LMNAMAPTALDH1A1MAPK1TDP1 | |
| SCHEMBL14597262 | 0.76 | LY96 (0.72) | SMN1; SMN2LMNAHSD17B3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021692-A1 | CURCUMIN ANALOGS AND METHODS OF USE THEREOF | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2012-02-16 | — | — | WO | disclosed |