Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.46 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL101142 | 0.93 | AKR1C3 (0.53) | MEN1LMNAGAAKMT2AL3MBTL1 | |
| SCHEMBL101215 | 0.88 | NPC1 (0.47) | MEN1LMNAGAAKMT2AL3MBTL1 | |
| SCHEMBL100918 | 0.88 | AKR1C3 (0.46) | MEN1KMT2AAKR1C3AKR1C2HDAC1 | |
| SCHEMBL98803 | 0.88 | POLB (0.50) | MEN1KMT2AL3MBTL1AKR1C3AKR1C2 | |
| SCHEMBL101223 | 0.85 | HDAC1 (0.51) | MEN1KMT2AAKR1C3AKR1C2HDAC1 | |
| SCHEMBL99412 | 0.83 | HCAR2 (0.47) | MEN1LMNAKMT2AAKR1C3AKR1C2 | |
| SCHEMBL662835 | 0.82 | CHRM3 (0.55) | — | |
| SCHEMBL101623 | 0.82 | HDAC2 (0.48) | MEN1KMT2AHDAC1SOAT1HCAR2 | |
| SCHEMBL99701 | 0.81 | AKR1C3 (0.53) | MEN1KMT2AAKR1C3AKR1C2HCAR2 | |
| SCHEMBL99615 | 0.81 | RAB9A (0.55) | MEN1LMNAGAAKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | claimed |