Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 6/20 | 0.86 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | CASP2 | P42575 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13268369 | 1.00 | FAAH (0.86) | FAAHGAAHSP90AA1DNM1EPHX2 | |
| SCHEMBL9618659 | 0.97 | FAAH (0.81) | FAAHGAAHSP90AA1DNM1EPHX2 | |
| SCHEMBL8204892 | 0.93 | FAAH (1.00) | FAAHHSP90AA1DNM1EPHX2CASP2 | |
| SCHEMBL3915907 | 0.93 | FAAH (1.00) | FAAHHSP90AA1DNM1EPHX2CASP2 | |
| SCHEMBL8210761 | 0.93 | FAAH (1.00) | FAAHHSP90AA1DNM1EPHX2CASP2 | |
| SCHEMBL4141617 | 0.93 | FAAH (1.00) | FAAHHSP90AA1DNM1EPHX2CASP2 | |
| SCHEMBL4147161 | 0.93 | FAAH (1.00) | FAAHHSP90AA1DNM1EPHX2CASP2 | |
| N-Ethylpalmitamide SCHEMBL4148137 | 0.93 | FAAH (1.00) | FAAHHSP90AA1DNM1EPHX2CASP2 | |
| SCHEMBL8205915 | 0.93 | FAAH (1.00) | FAAHHSP90AA1DNM1EPHX2CASP2 | |
| SCHEMBL11104897 | 0.93 | FAAH (1.00) | FAAHHSP90AA1DNM1EPHX2CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120077863-A1 | GUANIDINO-SUBSTITUTED BI-AND POLYPHENYLS AS SMALL MOLECULE CARRIERS | UCL BUSINESS PLC (GB) | 2012-03-29 | — | — | US | disclosed |
| WO-2010097604-A2 | NEW COMPOUNDS | UCL BUSINESS PLC (GB) | 2010-09-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120077863-A1 | GUANIDINO-SUBSTITUTED BI-AND POLYPHENYLS AS SMALL MOLECULE CARRIERS | CFTR, GNB1, GMPS | FAAH 3404/4885GAA 1952/4885HSP90AA1 3870/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.