SCHEMBL1006438

SCHEMBL1006438

Cc1ccccc1-c1ccc(-c2ccccc2C)c(O)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.59
APP P05067 1/20 0.54
PDK2 Q15119 1/20 0.50
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
ESR2 Q92731 2/20 0.47
TRPA1 O75762 1/20 0.45
CTSD P07339 1/20 0.45
BACE1 P56817 1/20 0.45
ESR1 P03372 1/20 0.44
HTR7 P34969 1/20 0.43
GRIA1 P42261 1/20 0.42
CACNG8 Q8WXS5 1/20 0.42
LCK P06239 1/20 0.42
KDR P35968 1/20 0.42
JAK3 P52333 1/20 0.42
MAPK14 Q16539 1/20 0.42
AR P10275 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14850873 0.88 APP (0.72) MCL1APPPDK2CA12CA1
SCHEMBL1007616 0.88 MCL1 (0.59) MCL1APPPDK2CA12CA1
SCHEMBL11037218 0.83 MCL1 (0.64) MCL1APPPDK2CA12CA1
SCHEMBL30158721 0.83 MCL1 (0.64) MCL1APPPDK2CA12CA1
SCHEMBL5843910 0.82 ALOX15 (0.57) MCL1APPPDK2CA12CA1
SCHEMBL2865467 0.81 ALOX5 (0.54) MCL1ESR2ESR1HPGDTP53
SCHEMBL9742749 0.81 MCL1 (0.51) MCL1APPPDK2CA12CA1
SCHEMBL8115899 0.80 MCL1 (0.50) MCL1PDK2CA12CA1CA2
SCHEMBL758202 0.80 HPGD (0.52) MCL1CA12CA1CA2CA9
SCHEMBL31337248 0.80 HPGD (0.52) MCL1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12421349-B2 Polyphenylene ether composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2025-09-23 US disclosed
EP-4039728-B1 POLYPHENYLENE ETHER COMPOSITION ASAHI CHEMICAL IND (JP) 2023-10-11 EP disclosed
WO-2022239631-A1 NOVEL TERMINAL-MODIFIED POLYPHENYLENE ETHER AND TERMINAL-MODIFIED POLYPHENYLENE ETHER COMPOSITION 旭化成株式会社 2022-11-17 WO disclosed
US-20220356302-A1 POLYPHENYLENE ETHER COMPOSITION ASAHI KASEI KABUSHIKI KAISHA (JP) 2022-11-10 US disclosed
EP-4039728-A1 POLYPHENYLENE ETHER COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2022-08-10 EP disclosed
CN-110387037-B Polyphenylene ether and process for producing the same 旭化成株式会社 2022-05-13 CN disclosed
CN-110078912-B Continuous pressure filtration washing method for polyphenyl ether 蓝星(北京)技术中心有限公司 2021-11-09 CN disclosed
EP-2628759-B1 POLYPHENYLENE ETHER AS WELL AS RESIN COMPOSITION AND MOLDING THEREOF ASAHI CHEMICAL IND (JP) 2021-06-30 EP disclosed
CN-112812291-A Hydrogenated polyphenylene ether and process for producing the same 旭化成株式会社 2021-05-18 CN disclosed
CN-108017791-B Polyphenylene ether powder and process for producing the same 旭化成株式会社 2021-02-02 CN disclosed
US-8865811-B2 2014-10-21 US disclosed
US-8637631-B2 Polyphenylene ether and method for producing the same ASAHI KASEI CHEMICALS CORPORATION (JP) 2014-01-28 US disclosed
US-20130245182-A1 POLYPHENYLENE ETHER POWDER AND POLYPHENYLENE ETHER RESIN COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-09-19 US disclosed
US-20130231430-A1 POLYPHENYLENE ETHER, RESIN COMPOSITION, AND MOLDED BODY OF RESIN COMPOSITION ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-09-05 US disclosed
EP-2628759-A1 POLYPHENYLENE ETHER AS WELL AS RESIN COMPOSITION AND MOLDING THEREOF Asahi Kasei Chemicals Corporation (JP) 2013-08-21 EP disclosed
EP-2628760-A1 POLYPHENYLENE ETHER POWDER AND POLYPHENYLENE ETHER COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2013-08-21 EP disclosed
US-8445573-B2 Polyphenylene ether resin composition having narrow molecular weight distribution ASAHI KASEI CHEMICALS CORPORATION (JP) 2013-05-21 US disclosed
US-20120309925-A1 POLYPHENYLENE ETHER AND METHOD FOR PRODUCING THE SAME ASAHI KASEI CHEMICALS CORPORATION (JP) 2012-12-06 US disclosed
US-20110166269-A1 POLYPHENYLENE ETHER RESIN COMPOSITION HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION ASAHI KASEI CHEMICALS CORPORATION (JP) 2011-07-07 US disclosed
EP-2277951-A1 POLYPHENYLENE ETHER RESIN COMPOSITION HAVING NARROW MOLECULAR WEIGHT DISTRIBUTION Asahi Kasei Chemicals Corporation (JP) 2011-01-26 EP disclosed