⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6562134 | 0.87 | LMNA (1.00) | — | |
| SCHEMBL17833860 | 0.86 | LMNA (0.58) | — | |
| SCHEMBL7904847 | 0.80 | — | — | |
| SCHEMBL15895028 | 0.79 | — | — | |
| SCHEMBL15298754 | 0.79 | LMNA (0.82) | — | |
| SCHEMBL836383 | 0.79 | LMNA (0.82) | — | |
| SCHEMBL17453143 | 0.79 | LMNA (0.48) | — | |
| SCHEMBL24347595 | 0.77 | LMNA (0.78) | — | |
| SCHEMBL14516809 | 0.77 | LMNA (0.78) | — | |
| SCHEMBL12989977 | 0.76 | LMNA (0.75) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220096646-A1 | SSTR-TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | TVA (ABC), LLC | 2022-03-31 | — | — | US | disclosed |
| US-20210379253-A1 | IMMOBILISED BIOLOGICAL ENTITIES | CARMEDA AB (SE) | 2021-12-09 | — | — | US | disclosed |
| US-10736999-B2 | Immobilised biological entities | W.L GORE & ASSOCIATES, INC. (US) | 2020-08-11 | — | — | US | disclosed |
| US-9764068-B2 | Immobilised biological entities | W.L. GORE AND ASSOCIATES INC. (US) | 2017-09-19 | — | — | US | disclosed |
| US-9474804-B2 | Poly(vinyl ester) polymers for in vivo nucleic acid delivery | Arrowhead Pharmaceuticals, Inc. (US) | 2016-10-25 | — | — | US | disclosed |
| US-20150290341-A1 | TARGETED IDURONATE-2-SULFATASE COMPOUNDS | Anglachem Inc. (CA) | 2015-10-15 | — | — | US | disclosed |
| US-20150283256-A1 | Poly(vinyl ester) Polymers for In Vivo Nucleic Acid Delivery | Arrowhead Pharmaceuticals, Inc. | 2015-10-08 | — | — | US | disclosed |
| US-9089611-B2 | Poly(vinyl ester) polymers for in vivo nucleic acid delivery | Arrowhead Madison Inc. (US) | 2015-07-28 | — | — | US | disclosed |
| US-20150110732-A1 | Poly(vinyl ester) Polymers for In Vivo Nucleic Acid Delivery | Arrowhead Madison Inc. | 2015-04-23 | — | — | US | disclosed |
| US-20150037311-A1 | TARGETED LYSOSOMAL ENZYME COMPOUNDS | ANGIOCHEM INC. (CA) | 2015-02-05 | — | — | US | disclosed |
| US-8932572-B2 | Poly(vinyl ester) polymers for in vivo nucleic acid delivery | Arrowhead Madison Inc. (US) | 2015-01-13 | — | — | US | disclosed |
| US-20140335163-A1 | TARGETED IDURONATE-2-SULFATASE COMPOUNDS | ANGIOCHEM INC. (CA) | 2014-11-13 | — | — | US | disclosed |
| US-20130121954-A1 | Poly(vinyl ester) Polymers for In Vivo Nucleic Acid Delivery | Arrowhead Madison Inc. (US) | 2013-05-16 | — | — | US | disclosed |
| WO-2013032829-A1 | POLY(VINYL ESTER) POLYMERS FOR IN VIVO NUCLEIC ACID DELIVERY | ARROWHEAD RESEARCH CORPORATION (US) | 2013-03-07 | — | — | WO | disclosed |
| US-20120020881-A1 | Triaryl-sulphonium compounds, kit and methods for labeling positron emitting isotopes | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2012-01-26 | — | — | US | disclosed |