Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 12/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29139211 | 0.86 | KDM4E (0.62) | NOTUMKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL10042664 | 0.85 | NOTUM (0.44) | NOTUMKDM4EMAPTALDH1A1LMNA | |
| SCHEMBL10299025 | 0.77 | NPC1 (0.53) | NOTUMKDM4EMAPTALDH1A1TSHR | |
| SCHEMBL2758572 | 0.76 | L3MBTL1 (0.62) | KDM4EMAPTALDH1A1LMNAHTT | |
| SCHEMBL9956092 | 0.75 | KDM4E (0.41) | NOTUMKDM4EMAPTALDH1A1TSHR | |
| SCHEMBL16605606 | 0.74 | L3MBTL1 (0.60) | KDM4EMAPTALDH1A1LMNAHTT | |
| SCHEMBL12754466 | 0.74 | L3MBTL1 (0.60) | KDM4EMAPTALDH1A1LMNAHTT | |
| SCHEMBL13144266 | 0.74 | L3MBTL1 (0.60) | KDM4EMAPTALDH1A1LMNAHTT | |
| SCHEMBL23534547 | 0.74 | KDM4E (0.71) | KDM4EMAPTALDH1A1LMNAHTT | |
| SCHEMBL29362582 | 0.74 | KDM4E (0.71) | KDM4EMAPTALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012088316-A1 | 2-ALKYL-5-PHENYL OXADIAZOLE-CARBAZOLE HOSTS FOR GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |