Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | SI | P14410 | 3/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10299025 | 0.85 | NPC1 (0.53) | KDM4EATML3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL10064523 | 0.84 | NPC1 (0.40) | KDM4EATML3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL10064466 | 0.79 | HDAC6 (0.47) | KDM4EATML3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL10820029 | 0.78 | SMN1; SMN2 (0.52) | KDM4EATML3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL2730054 | 0.78 | GUSB (0.40) | KDM4EATML3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL2718884 | 0.78 | KDM4E (0.53) | KDM4ESMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL18196326 | 0.78 | ALDH1A1 (0.40) | KDM4EATML3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL21312049 | 0.77 | KDM4E (0.48) | KDM4EATML3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL11934023 | 0.76 | SMN1; SMN2 (0.61) | KDM4EATML3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL10820027 | 0.75 | NPC1 (0.56) | KDM4ESMN1; SMN2RAB9AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012088316-A1 | 2-ALKYL-5-PHENYL OXADIAZOLE-CARBAZOLE HOSTS FOR GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |
| WO-2012088316-A1 | 2-ALKYL-5-PHENYL OXADIAZOLE-CARBAZOLE HOSTS FOR GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |