Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 5/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10064304 | 0.82 | PSMD14 (0.50) | PSMD14LMNATP53CYP19A1HDAC1 | |
| SCHEMBL13709261 | 0.77 | KDM4E (0.44) | KMT2A | |
| SCHEMBL12846413 | 0.76 | KDM4E (0.46) | — | |
| SCHEMBL19452419 | 0.76 | KDM4E (0.39) | — | |
| SCHEMBL21765759 | 0.76 | CA1 (0.52) | CA1CA2CYP19A1HTR6HDAC1 | |
| SCHEMBL13589826 | 0.75 | KDM4E (0.36) | LMNATP53MAPT | |
| SCHEMBL26058165 | 0.74 | GPR3 (0.39) | LMNAMEN1KMT2AMAPT | |
| SCHEMBL10138547 | 0.74 | KDM4E (0.31) | — | |
| SCHEMBL17636194 | 0.73 | KDM4E (0.36) | — | |
| SCHEMBL19114596 | 0.73 | KDM4E (0.40) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012088316-A1 | 2-ALKYL-5-PHENYL OXADIAZOLE-CARBAZOLE HOSTS FOR GUEST EMITTERS | GEORGIA TECH RESEARCH CORPORATION (US) | 2012-06-28 | — | — | WO | disclosed |