Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | GPR174 | Q9BXC1 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19501001 | 0.84 | NPC1 (0.67) | RXFP1TDP1KDM4EALDH1A1NPC1 | |
| SCHEMBL219147 | 0.83 | KDM4E (0.66) | RXFP1TDP1KDM4EALDH1A1NPC1 | |
| SCHEMBL201861 | 0.83 | RXFP1 (0.54) | RXFP1TDP1KDM4EALDH1A1NPC1 | |
| SCHEMBL166821 | 0.80 | MAPT (0.67) | RXFP1TDP1KDM4EALDH1A1NPC1 | |
| Dimethylamine SCHEMBL10625504 | 0.80 | KDM4E (0.61) | RXFP1TDP1KDM4EALDH1A1NPC1 | |
| SCHEMBL13446819 | 0.79 | TDP1 (0.43) | RXFP1TDP1KDM4EALDH1A1NPC1 | |
| Trimethylammonium SCHEMBL11436463 | 0.79 | KDM4E (0.59) | RXFP1TDP1KDM4EALDH1A1NPC1 | |
| SCHEMBL12464035 | 0.78 | RAB9A (0.41) | RXFP1TDP1KDM4EALDH1A1NPC1 | |
| SCHEMBL439393 | 0.78 | RXFP1 (0.74) | RXFP1TDP1KDM4EALDH1A1NPC1 | |
| SCHEMBL9011492 | 0.77 | KDM4E (0.58) | RXFP1TDP1KDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110338-B2 | Heat-sensitive positive-working lithographic printing plate precursor | AGFA GRAPHICS NV (BE) | 2012-02-07 | — | — | US | disclosed |
| US-20090170028-A1 | HEAT-SENSITIVE POSITIVE-WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR | AGFA GRAPHICS NV (BE) | 2009-07-02 | — | — | US | disclosed |