SCHEMBL439393

SCHEMBL439393

C=C(C)C(=O)Nc1ccc(NC(=O)C(=C)C)cc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.74
TDP1 Q9NUW8 3/20 0.60
L3MBTL1 Q9Y468 4/20 0.53
POLB P06746 3/20 0.53
RECQL P46063 1/20 0.53
BLM P54132 1/20 0.53
BAZ1A Q9NRL2 1/20 0.51
ALDH1A1 P00352 4/20 0.50
KDM4E B2RXH2 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
HTT P42858 1/20 0.50
KMT2A Q03164 3/20 0.48
MEN1 O00255 2/20 0.48
MAPT P10636 2/20 0.48
CA12 O43570 1/20 0.48
BRD4 O60885 1/20 0.48
NR1I2 O75469 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
MB P02144 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17084525 0.93 RXFP1 (0.67) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL959539 0.91 RXFP1 (0.65) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL124216 0.91 RXFP1 (0.65) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL6834332 0.89 RXFP1 (0.62) RXFP1TDP1L3MBTL1POLBRECQL
Hydrochloric Acid SCHEMBL7460090 0.89 RXFP1 (0.62) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL7800028 0.89 TDP1 (0.66) RXFP1TDP1L3MBTL1POLBALDH1A1
SCHEMBL17299114 0.89 RXFP1 (0.62) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL8164496 0.89 RXFP1 (0.62) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL5071228 0.89 RXFP1 (0.62) RXFP1TDP1L3MBTL1POLBRECQL
SCHEMBL3298240 0.89 RXFP1 (0.62) RXFP1TDP1L3MBTL1POLBRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025061713-A1 COMPOSITION AND METHOD OF 3D PRINTING A POROUS, SUBSTANCE-EMBOSSED MATERIAL, POROUS, SUBSTANCE-EMBOSSED MATERIAL, AND USES THEREOF UNIVERSITÄT ULM (DE) 2025-03-27 WO claimed
EP-2938641-B1 MOLECULARLY IMPRINTED POLYMERS AND THEIR USE AS ANTIDANDRUFF AGENTS ORÉAL L (FR) 2016-08-24 EP claimed
US-7071240-B1 Carboxylic cationites and methods of manufacture POLYGRAN LTD. (IL) 2006-07-04 US claimed
US-20040062745-A1 Molecularly imprinted polymers for the treatment and diagnosis of medical conditions GREEN BERNARD S (IL) 2004-04-01 US claimed
US-6638498-B2 A compound, comprising a molecularly imprinted polymer featuring at least one functional monomer selected from the vinyl hydroxypyridine; monomers selected from 4-vinylbenzamide and N-alkyl or N,N-dialkyl derivatives SEMOREX INC. 2003-10-28 US claimed
US-20020015690-A1 Molecularly imprinted polymers for the treatment and diagnosis of medical conditions SEMOREX INC. 2002-02-07 US claimed
WO-2025061713-A1 COMPOSITION AND METHOD OF 3D PRINTING A POROUS, SUBSTANCE-EMBOSSED MATERIAL, POROUS, SUBSTANCE-EMBOSSED MATERIAL, AND USES THEREOF UNIVERSITÄT ULM (DE) 2025-03-27 WO disclosed
US-20230190613-A1 SKIN PERFECTING COSMETIC COMPOSITIONS AND METHODS OF USE L'OREAL (FR) 2023-06-22 US disclosed
WO-2022261721-A1 HEALABLE AND REPROCESSABLE COMPOSITIONS DEAKIN UNIVERSITY (AU) 2022-12-22 WO disclosed
EP-3313566-B1 PREPARATION OF MOLECULARLY IMPRINTED POLYMERS BY TWO-PHOTON STEREOLITHOGRAPHY CENTRE NAT RECH SCIENT (FR) 2019-06-05 EP disclosed
US-9983441-B2 Liquid crystal display device MERCK PATENT GMBH (DE) 2018-05-29 US disclosed
EP-3313566-A1 PREPARATION OF MOLECULARLY IMPRINTED POLYMERS BY TWO-PHOTON STEREOLITHOGRAPHY Centre National De La Recherche Scientifique (FR) 2018-05-02 EP disclosed
WO-2017001451-A1 PREPARATION OF MOLECULARLY IMPRINTED POLYMERS BY TWO-PHOTON STEREOLITHOGRAPHY CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2017-01-05 WO disclosed
US-20040062745-A1 Molecularly imprinted polymers for the treatment and diagnosis of medical conditions GREEN BERNARD S (IL) 2004-04-01 US disclosed
US-6638498-B2 A compound, comprising a molecularly imprinted polymer featuring at least one functional monomer selected from the vinyl hydroxypyridine; monomers selected from 4-vinylbenzamide and N-alkyl or N,N-dialkyl derivatives SEMOREX INC. 2003-10-28 US disclosed
US-20020160295-A1 Recording negatives; lithography printing plates; mixture of addiiton polymer and binder FUJIFILM CORPORATION (JP) 2002-10-31 US disclosed
EP-1235107-A1 Photopolymerizable composition FUJI PHOTO FILM CO., LTD. (JP) 2002-08-28 EP disclosed
US-20020015690-A1 Molecularly imprinted polymers for the treatment and diagnosis of medical conditions SEMOREX INC. 2002-02-07 US disclosed
US-4384011-A Process for producing gravure printing plates DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) 1983-05-17 US disclosed
US-4021404-A AMIDES, NATURAL AND SYNTHETIC RUBBERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-05-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230190613-A1 SKIN PERFECTING COSMETIC COMPOSITIONS AND METHODS OF USE CUTA, ELOVL3, ELOVL1 RXFP1 2400/4885TDP1 1468/4885L3MBTL1 1843/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.