Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | XIAP | P98170 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10065686 | 0.92 | MAPT (0.50) | L3MBTL1HTTKDM4EALDH1A1GAA | |
| SCHEMBL10065109 | 0.87 | NOTUM (0.56) | NPSR1FFAR1TSHRITGB1ITGA4 | |
| SCHEMBL10065065 | 0.86 | HTT (0.70) | L3MBTL1HTTKDM4EALDH1A1GAA | |
| SCHEMBL10065073 | 0.86 | NPSR1 (0.49) | HTTNPSR1FFAR1LMNAITGB1 | |
| SCHEMBL10065111 | 0.86 | NPSR1 (0.68) | ALDH1A1GAANPSR1MAPTFFAR1 | |
| SCHEMBL10065684 | 0.86 | NPSR1 (0.49) | HTTNPSR1FFAR1LMNAITGB1 | |
| SCHEMBL10065721 | 0.85 | HTT (0.52) | L3MBTL1HTTKDM4EALDH1A1GAA | |
| SCHEMBL15692434 | 0.85 | FFAR1 (0.51) | L3MBTL1HTTKDM4EALDH1A1GAA | |
| SCHEMBL10065066 | 0.84 | HTT (0.56) | L3MBTL1HTTKDM4EALDH1A1GAA | |
| SCHEMBL10065685 | 0.84 | KMT2A (0.64) | HTTALDH1A1GAAMAPTFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004269-A1 | (2-ARYLOXY-ACETYLAMINO)-PHENYL-PROPIONIC ACID DERIVATIVES, METHOD FOR PRODUCING SAME AND USE THEREOF AS PHARMACEUTICALS | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |