Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.68 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10065109 | 0.87 | NOTUM (0.56) | NPSR1FFAR1TDP1ITGB1ITGA4 | |
| SCHEMBL10065684 | 0.86 | NPSR1 (0.49) | NPSR1FFAR1TP53LMNASMN1; SMN2 | |
| SCHEMBL10065073 | 0.86 | NPSR1 (0.49) | NPSR1FFAR1TP53LMNASMN1; SMN2 | |
| SCHEMBL10065067 | 0.86 | L3MBTL1 (0.56) | NPSR1FFAR1LMNAALDH1A1GAA | |
| SCHEMBL15692462 | 0.85 | NPSR1 (0.60) | NPSR1FFAR1TP53LMNASMN1; SMN2 | |
| SCHEMBL10065685 | 0.84 | KMT2A (0.64) | FFAR1LMNAALDH1A1GAAMAPT | |
| SCHEMBL10065686 | 0.83 | MAPT (0.50) | NPSR1FFAR1ALDH1A1GAAMAPT | |
| SCHEMBL10064941 | 0.78 | ITGB1 (0.46) | FFAR1MAPTITGB1ITGA4MEN1 | |
| SCHEMBL10064980 | 0.78 | KMT2A (0.53) | NPSR1FFAR1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL10065063 | 0.77 | HSD11B1 (0.49) | NPSR1FFAR1TP53LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004269-A1 | (2-ARYLOXY-ACETYLAMINO)-PHENYL-PROPIONIC ACID DERIVATIVES, METHOD FOR PRODUCING SAME AND USE THEREOF AS PHARMACEUTICALS | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |