Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CRHBP | P24387 | 1/20 | 0.52 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3162742 | 0.89 | KMT2A (0.51) | KMT2AMEN1RXFP1POLBTSHR | |
| SCHEMBL10064814 | 0.89 | KMT2A (0.51) | KMT2AMEN1RXFP1POLBTSHR | |
| SCHEMBL10064815 | 0.88 | KMT2A (0.64) | KMT2AMEN1RXFP1POLBTSHR | |
| SCHEMBL10064976 | 0.86 | MEN1 (0.47) | KMT2AMEN1RXFP1POLBTSHR | |
| SCHEMBL10065062 | 0.86 | FFAR1 (0.62) | KMT2AMEN1RXFP1POLBTSHR | |
| SCHEMBL10064818 | 0.85 | FFAR1 (0.53) | KMT2AMEN1RXFP1POLBTSHR | |
| SCHEMBL10065109 | 0.85 | NOTUM (0.56) | KMT2AMEN1RXFP1POLBTSHR | |
| SCHEMBL10065111 | 0.84 | NPSR1 (0.68) | KMT2AMEN1RXFP1FFAR1ALDH1A1 | |
| SCHEMBL10065067 | 0.84 | L3MBTL1 (0.56) | TSHRFFAR1HTTALDH1A1MAPT | |
| SCHEMBL10065073 | 0.84 | NPSR1 (0.49) | KMT2AMEN1RXFP1POLBFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012004269-A1 | (2-ARYLOXY-ACETYLAMINO)-PHENYL-PROPIONIC ACID DERIVATIVES, METHOD FOR PRODUCING SAME AND USE THEREOF AS PHARMACEUTICALS | SANOFI (FR) | 2012-01-12 | — | — | WO | disclosed |