Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 5/20 | 1.00 |
| ▸ | AXL | P30530 | 2/20 | 1.00 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.52 |
| ▸ | JAK2 | O60674 | 2/20 | 0.52 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.52 |
| ▸ | IGF1R | P08069 | 2/20 | 0.52 |
| ▸ | IKBKB | O14920 | 1/20 | 0.52 |
| ▸ | CHUK | O15111 | 1/20 | 0.52 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.52 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.52 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.52 |
| ▸ | PAK4 | O96013 | 1/20 | 0.52 |
| ▸ | CSF1R | P07333 | 1/20 | 0.52 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | FLT1 | P17948 | 1/20 | 0.52 |
| ▸ | LTK | P29376 | 1/20 | 0.52 |
| ▸ | GRK5 | P34947 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29431037 | 1.00 | PRKCI (1.00) | PRKCIAXLDYRK1BJAK2AURKB | |
| SCHEMBL28757490 | 0.91 | PRKCI (0.82) | PRKCIAXLDYRK1BJAK2AURKB | |
| SCHEMBL11889555 | 0.85 | PRKCI (0.72) | PRKCIAXLDYRK1BJAK2AURKB | |
| SCHEMBL2240671 | 0.77 | AURKB (0.71) | PRKCIAXLDYRK1BJAK2AURKB | |
| SCHEMBL12613153 | 0.76 | PRKCI (0.61) | PRKCIAXLDYRK1BJAK2AURKB | |
| SCHEMBL4793014 | 0.76 | IGF1R (0.63) | PRKCIAXLDYRK1BJAK2AURKB | |
| SCHEMBL12127566 | 0.76 | NUDT1 (0.61) | PRKCIAXLDYRK1BJAK2AURKB | |
| SCHEMBL858771 | 0.74 | PRKCI (0.59) | PRKCIAXLDYRK1BJAK2AURKB | |
| SCHEMBL21062776 | 0.74 | PRKCI (0.59) | PRKCIAXLDYRK1BJAK2AURKB | |
| SCHEMBL1176829 | 0.74 | PRKCI (0.59) | PRKCIAXLDYRK1BJAK2AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1888 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117304068-A | Preparation method for synthesizing 2, 2-diisopropyl propionitrile from 2, 3-dimethylbutyramide | 濮阳天源生物科技有限公司 | 2023-12-29 | — | — | CN | claimed |
| CN-112867716-A | Solid forms of FGFR inhibitors and methods for their preparation | 因赛特公司 | 2021-05-28 | — | — | CN | claimed |
| CN-213229675-U | Reagent storage device for preparing 4-chloro-7-azaindole | 南通雅本化学有限公司 | 2021-05-18 | — | — | CN | claimed |
| CN-212720612-U | Drying device is used in production of 4-chlorine-7-azaindole | 南通雅本化学有限公司 | 2021-03-16 | — | — | CN | claimed |
| EP-3788047-A2 | SOLID FORMS OF AN FGFR INHIBITOR AND PROCESSES FOR PREPARING THE SAME | Incyte Corporation (US) | 2021-03-10 | — | — | EP | claimed |
| CN-111499676-A | 4-chloro-3-nitro-1-p-toluenesulfonyl-7-azaindole derivative and preparation method and application thereof | 绍兴文理学院 | 2020-08-07 | — | — | CN | claimed |
| US-20190337948-A1 | SOLID FORMS OF AN FGFR INHIBITOR AND PROCESSES FOR PREPARING THE SAME | WILMINGTON PHARMATECH | 2019-11-07 | — | — | US | claimed |
| EP-2855473-B1 | PROCESS FOR PREPARING INTERMEDIATES COMPOUND | GENENTECH INC (US) | 2018-10-03 | — | — | EP | claimed |
| CN-105777747-A | 4-chloro-7-azaindole and preparation method thereof | 叶芳 | 2016-07-20 | — | — | CN | claimed |
| US-9221813-B2 | Intermediates and processes for preparing compounds | GENENTECH, INC. (US) | 2015-12-29 | — | — | US | claimed |
| US-20150105557-A1 | INTERMEDIATES AND PROCESSES FOR PREPARING COMPOUNDS | GENENTECH, INC. | 2015-04-16 | — | — | US | claimed |
| EP-2855473-A1 | INTERMEDIATES AND PROCESSES FOR PREPARING COMPOUNDS | Genentech, Inc. (US) | 2015-04-08 | — | — | EP | claimed |
| WO-2013163109-A1 | INTERMEDIATES AND PROCESSES FOR PREPARING COMPOUNDS | GENENTECH, INC. (US) | 2013-10-31 | — | — | WO | claimed |
| EP-4747250-A1 | KINASE INHIBITORS | The United States Of America, As Represented By The Secretary, Department of Health and Human Services (US) | 2026-05-27 | — | — | EP | disclosed |
| CN-116496219-B | Six-membered and five-membered heterocyclic compound, and pharmaceutical composition and application thereof | 东南大学 | 2026-05-15 | — | — | CN | disclosed |
| US-20260125379-A1 | PRODRUG OF JAK KINASE INHIBITOR | E NITIATE BIOPHARMACEUTICALS HANGZHOU CO LTD (CN) | 2026-05-07 | — | — | US | disclosed |
| EP-1218348-A2 | INDAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEIN KINASES, AND METHODS FOR THEIR USE | AGOURON PHARMACEUTICALS, INC. (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2002012240-A1 | DERIVATIVES OF VARIOLIN B | UNIVERSIDAD DE BARCELONA (ES) | 2002-02-14 | — | — | WO | disclosed |
| WO-2001046196-A1 | 4-SUBSTITUTED 7-AZA-INDOLIN-2-ONES AND THEIR USE AS PROTEIN KINASE INHIBITORS | SUGEN, INC. (US) | 2001-06-28 | — | — | WO | disclosed |
| WO-2001002369-A2 | INDAZOLE COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS FOR INHIBITING PROTEIN KINASES, AND METHODS FOR THEIR USE | AGOURON PHARMACEUTICALS, INC. (US) | 2001-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105557-A1 | INTERMEDIATES AND PROCESSES FOR PREPARING COMPOUNDS | CHEK1, CHEK2, PLK1 | PRKCI 201/4885AXL 1353/4885DYRK1B 2168/4885 |
| US-20190337948-A1 | SOLID FORMS OF AN FGFR INHIBITOR AND PROCESSES FOR PREPARING THE SAME | FGFR1, FGFR2, FGFR3 | PRKCI 718/4885AXL 15/4885DYRK1B 178/4885 |
| US-20260125379-A1 | PRODRUG OF JAK KINASE INHIBITOR | JAK1, JAK2, JAK3 | PRKCI 286/4885AXL 103/4885DYRK1B 349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.