Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 4/20 | 0.68 |
| ▸ | POLB | P06746 | 4/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | FLT3 | P36888 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TERT | O14746 | 3/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MERTK | Q12866 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1289391 | 0.89 | RAD52 (0.59) | RAD52POLBRXFP1ALDH1A1MAPK1 | |
| SCHEMBL1289430 | 0.89 | ALDH1A1 (0.65) | RAD52POLBRXFP1ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL4512267 | 0.89 | RAD52 (0.61) | RAD52POLBRXFP1ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL4507791 | 0.89 | RAD52 (0.61) | RAD52POLBRXFP1ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL4507915 | 0.88 | ALDH1A1 (0.67) | RAD52POLBRXFP1ALDH1A1MAPK1 | |
| SCHEMBL12473363 | 0.86 | ALDH1A1 (0.60) | RAD52POLBRXFP1ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL4500478 | 0.85 | ALDH1A1 (0.62) | RAD52POLBRXFP1ALDH1A1MAPK1 | |
| SCHEMBL1289449 | 0.82 | ALDH1A1 (0.59) | RAD52POLBRXFP1ALDH1A1MAPK1 | |
| SCHEMBL4510629 | 0.82 | POLB (0.66) | RAD52POLBRXFP1ALDH1A1MAPK1 | |
| Hydrochloric Acid SCHEMBL4509844 | 0.82 | RAD52 (0.66) | RAD52POLBRXFP1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |