Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | RAD52 | P43351 | 5/20 | 0.56 |
| ▸ | POLB | P06746 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 8/20 | 0.48 |
| ▸ | TOP2A | P11388 | 2/20 | 0.47 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | ACP1 | P24666 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1289520 | 0.89 | FLT3 (0.53) | ALDH1A1MAPK1RAD52POLBKMT2A | |
| SCHEMBL1289430 | 0.89 | ALDH1A1 (0.65) | ALDH1A1MAPK1RAD52POLBKMT2A | |
| Hydrochloric Acid SCHEMBL4509844 | 0.88 | RAD52 (0.66) | ALDH1A1MAPK1RAD52POLBKMT2A | |
| SCHEMBL4510629 | 0.88 | POLB (0.66) | ALDH1A1MAPK1RAD52POLBKMT2A | |
| Hydrochloric Acid SCHEMBL4508209 | 0.88 | ALDH1A1 (0.53) | ALDH1A1MAPK1RAD52POLBKMT2A | |
| Hydrochloric Acid SCHEMBL4507915 | 0.88 | ALDH1A1 (0.67) | ALDH1A1MAPK1RAD52POLBKMT2A | |
| Hydrochloric Acid SCHEMBL4498567 | 0.87 | ALDH1A1 (0.53) | ALDH1A1MAPK1RAD52POLBKMT2A | |
| SCHEMBL12473363 | 0.86 | ALDH1A1 (0.60) | ALDH1A1MAPK1RAD52POLBKMT2A | |
| Hydrochloric Acid SCHEMBL4500478 | 0.85 | ALDH1A1 (0.62) | ALDH1A1MAPK1RAD52POLBKMT2A | |
| SCHEMBL10065462 | 0.82 | RAD52 (0.68) | ALDH1A1MAPK1RAD52POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090318479-A1 | SUBSTITUTED RING FUSED AZINES AND THEIR USE IN CANCER THERAPY | AUCKLAND UNISERVICES LIMITED | 2009-12-24 | — | — | US | claimed |
| US-20090318479-A1 | SUBSTITUTED RING FUSED AZINES AND THEIR USE IN CANCER THERAPY | AUCKLAND UNISERVICES LIMITED | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318479-A1 | SUBSTITUTED RING FUSED AZINES AND THEIR USE IN CANCER THERAPY | TP53, AZI2, MCL1 | ALDH1A1 217/4885MAPK1 4692/4885RAD52 611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.