Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | RAD52 | P43351 | 4/20 | 0.72 |
| ▸ | POLB | P06746 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.64 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.61 |
| ▸ | KDM1A | O60341 | 1/20 | 0.60 |
| ▸ | ACP1 | P24666 | 2/20 | 0.59 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | PDE5A | O76074 | 2/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | TOP2A | P11388 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4502640 | 0.99 | MAPK1 (0.79) | MAPK1ALDH1A1RAD52POLBKMT2A | |
| SCHEMBL10065464 | 0.86 | ALDH1A1 (0.76) | MAPK1ALDH1A1RAD52POLBKMT2A | |
| Hydrochloric Acid SCHEMBL4511057 | 0.85 | MAPK1 (0.78) | MAPK1ALDH1A1RAD52POLBKMT2A | |
| SCHEMBL1085391 | 0.81 | TLR9 (0.95) | MAPK1ALDH1A1RAD52POLBKMT2A | |
| SCHEMBL29713600 | 0.81 | TLR9 (0.95) | MAPK1ALDH1A1RAD52POLBKMT2A | |
| SCHEMBL1289375 | 0.80 | KDM1A (0.54) | MAPK1ALDH1A1RAD52POLBKMT2A | |
| Hydrochloric Acid SCHEMBL4505205 | 0.79 | KDM1A (0.53) | MAPK1ALDH1A1RAD52POLBKMT2A | |
| SCHEMBL23748376 | 0.79 | MAPK1 (0.74) | MAPK1ALDH1A1RAD52POLBKMT2A | |
| SCHEMBL26639503 | 0.79 | MAPK1 (0.74) | MAPK1ALDH1A1RAD52POLBKMT2A | |
| SCHEMBL5047707 | 0.78 | TLR9 (1.00) | MAPK1ALDH1A1RAD52POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012046207-A1 | ANTI-PARASITIC SUBSTITUTED RING FUSED AZINE COMPOUNDS | PARACO TECHNOLOGY LIMITED (NZ) | 2012-04-12 | — | — | WO | disclosed |