Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | DHFR | P00374 | 4/20 | 0.36 |
| ▸ | ATIC | P31939 | 3/20 | 0.36 |
| ▸ | GART | P22102 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10065665 | 0.91 | TYMS (0.57) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL10065545 | 0.90 | TYMS (0.60) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL12801299 | 0.85 | TYMS (0.61) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL12801597 | 0.84 | TYMS (0.63) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL18709164 | 0.84 | KDM4E (0.47) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL12801446 | 0.83 | TYMS (0.67) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL2620981 | 0.80 | TYMS (0.71) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL16386323 | 0.80 | TYMS (0.71) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL12801454 | 0.80 | TYMS (0.58) | TYMSKDM4EMEN1ALDH1A1POLB | |
| SCHEMBL14342341 | 0.80 | TYMS (0.70) | TYMSKDM4EMEN1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120009124-A1 | USE OF BUFFERS FOR RADIONUCLIDE COMPLEXATION | GUERBET (FR) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120009124-A1 | USE OF BUFFERS FOR RADIONUCLIDE COMPLEXATION | CA5B, CA3, CA1 | TYMS 2924/4885KDM4E 4795/4885MEN1 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.