SCHEMBL10065668

SCHEMBL10065668

CCC(CC(C)OC(C)=O)OC(C)=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.47
CHRM2 P08172 1/20 0.47
CHRM4 P08173 1/20 0.47
CHRM1 P11229 1/20 0.47
TBXA2R P21731 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.45
GALR3 O60755 1/20 0.45
MAPT P10636 1/20 0.45
BLM P54132 1/20 0.45
LMNA P02545 2/20 0.36
MEN1 O00255 1/20 0.36
CYP1A2 P05177 1/20 0.36
HRH1 P35367 1/20 0.36
KMT2A Q03164 1/20 0.36
SLC18A3 Q16572 1/20 0.35
ALOX15 P16050 1/20 0.34
PRKCA P17252 2/20 0.34
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
TRPV1 Q8NER1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15725513 0.96 TSHR (0.44) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL10168449 0.96 TSHR (0.44) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL19760880 0.96 TSHR (0.44) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL28464334 0.88 TSHR (0.39) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL26338531 0.88 TSHR (0.39) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL15500033 0.87 TSHR (0.40) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL17358635 0.86 TSHR (0.50) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL14088060 0.84 TSHR (0.44) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL14088063 0.84 TSHR (0.44) TSHRCHRM2CHRM4CHRM1TBXA2R
SCHEMBL8465750 0.84 TSHR (0.38) TSHRCHRM2CHRM4CHRM1TBXA2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9110243-B2 Laminate film, optically compensatory film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2015-08-18 US disclosed
US-9040219-B2 Image forming material, planographic printing plate precursor, and method for manufacturing a planographic printing plate FUJIFILM CORPORATION (JP) 2015-05-26 US disclosed
US-8728591-B2 Polymer film, phase difference film, polarizing plate, liquid crystal display device, retardation inducing agent, and merocyanine-based compound FUJIFILM CORPORATION (JP) 2014-05-20 US disclosed
US-8440300-B2 Coated polyoxymethylenes BASF SE (DE) 2013-05-14 US disclosed
US-8426023-B2 Coated polyoxymethylenes comprising a formaldehyde scavenger comprising a lysine compound BASF SE (DE) 2013-04-23 US disclosed
US-20120329974-A1 POLYMER FILM, PHASE DIFFERENCE FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE, RETARDATION INDUCING AGENT, AND MEROCYANINE-BASED COMPOUND FUJIFILM CORPORATION (JP) 2012-12-27 US disclosed
US-20120251781-A1 LAMINATE FILM, OPTICALLY COMPENSATORY FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-10-04 US disclosed
US-20120052445-A1 IMAGE FORMING MATERIAL, PLANOGRAPHIC PRINTING PLATE PRECURSOR, AND METHOD FOR MANUFACTURING A PLANOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2012-03-01 US disclosed
US-8110010-B2 Coated coloring agents HENKEL AG & CO. KGAA (DE) 2012-02-07 US disclosed
US-20110247149-A1 Coated Coloring Agents HENKEL AG & CO. KGAA (DE) 2011-10-13 US disclosed
US-8029912-B2 Coated polyoxymethylenes BASF SE (DE) 2011-10-04 US disclosed
US-20100324184-A1 COATED POLYOXYMETHYLENES BASF SE (DE) 2010-12-23 US disclosed
US-20100316865-A1 COATED POLYOXYMETHYLENES BASF SE (DE) 2010-12-16 US disclosed
US-20100291389-A1 COATED POLYOXYMETHYLENES BASF SE PATENTS, TRADEMARKS AND LICENSES (DE) 2010-11-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120329974-A1 POLYMER FILM, PHASE DIFFERENCE FILM, POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE, RETARDATION INDUCING AGENT, AND MEROCYANINE-BASED COMPOUND PITHD1, CCNH, TRRAP TSHR 1775/4885CHRM2 4379/4885CHRM4 4275/4885
US-20110247149-A1 Coated Coloring Agents KRT18, CUTA, PORCN TSHR 4814/4885CHRM2 4043/4885CHRM4 4190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.