Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 9/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15744226 | 0.87 | ALOX5 (0.54) | ALOX5PTGES | |
| SCHEMBL23940981 | 0.81 | ALOX5 (0.40) | PSEN1ALOX5PTGES | |
| SCHEMBL9882380 | 0.81 | ALOX5 (0.40) | PSEN1ALOX5PTGES | |
| SCHEMBL24632221 | 0.73 | ALOX5 (0.49) | ALOX5 | |
| SCHEMBL23941478 | 0.72 | ALOX5 (0.35) | PSEN1ALOX5PTGES | |
| SCHEMBL9880202 | 0.72 | ALOX5 (0.45) | PSEN1ALOX5PTGES | |
| SCHEMBL9880204 | 0.72 | ALOX5 (0.45) | PSEN1ALOX5PTGES | |
| SCHEMBL9880203 | 0.72 | APP (0.34) | PSEN1ALOX5PTGESACHE | |
| SCHEMBL13663952 | 0.72 | ALOX5 (0.35) | PSEN1ALOX5PTGES | |
| SCHEMBL9880206 | 0.72 | ALOX5 (0.44) | PSEN1ALOX5PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2452679-A1 | CYTOPROTECTIVE AGENT | National University Corporation Tokyo University Of Agriculture and Technology (JP) | 2012-05-16 | — | — | EP | disclosed |