Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 17/20 | 0.54 |
| ▸ | PTGES | O14684 | 2/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24632221 | 0.87 | ALOX5 (0.49) | ALOX5NR1I2PPARGPPARA | |
| SCHEMBL10065701 | 0.87 | PSEN1 (0.40) | ALOX5PTGES | |
| SCHEMBL9882380 | 0.86 | ALOX5 (0.40) | ALOX5PTGESNR1I2 | |
| SCHEMBL23940981 | 0.86 | ALOX5 (0.40) | ALOX5PTGESNR1I2 | |
| SCHEMBL24632197 | 0.80 | ALOX5 (0.43) | ALOX5NR1I2PPARGPPARA | |
| SCHEMBL24221316 | 0.80 | ALOX5 (0.44) | ALOX5PTGESNR1I2PPARGPPARA | |
| SCHEMBL23941478 | 0.78 | ALOX5 (0.35) | ALOX5PTGESNR1I2PPARGPPARA | |
| SCHEMBL9880202 | 0.77 | ALOX5 (0.45) | ALOX5PTGES | |
| SCHEMBL9880204 | 0.77 | ALOX5 (0.45) | ALOX5PTGES | |
| SCHEMBL13663952 | 0.77 | ALOX5 (0.35) | ALOX5PTGESNR1I2PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2452679-B1 | TRIPRENYLPHENOLIC CYTOPROTECTIVE AGENT | UNIV TOKYO NAT UNIV CORP (JP) | 2014-05-28 | — | — | EP | disclosed |