Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 17/20 | 0.52 |
| ▸ | EDNRB | P24530 | 11/20 | 0.52 |
| ▸ | DHPS | P49366 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7787027 | 0.85 | EDNRA (0.53) | EDNRAEDNRBDHPS | |
| SCHEMBL7793953 | 0.84 | EDNRA (0.64) | EDNRAEDNRBDHPS | |
| SCHEMBL1009078 | 0.84 | EDNRA (0.66) | EDNRAEDNRBDHPS | |
| SCHEMBL8007885 | 0.83 | EDNRA (0.55) | EDNRAEDNRBDHPS | |
| SCHEMBL1009939 | 0.82 | EDNRA (0.54) | EDNRAEDNRB | |
| SCHEMBL7793803 | 0.82 | EDNRA (0.51) | EDNRAEDNRBDHPS | |
| SCHEMBL1008387 | 0.82 | EDNRA (0.53) | EDNRAEDNRBDHPS | |
| SCHEMBL2489314 | 0.82 | EDNRA (0.53) | EDNRAEDNRBDHPS | |
| SCHEMBL2489880 | 0.81 | EDNRA (0.56) | EDNRAEDNRB | |
| SCHEMBL2490097 | 0.81 | EDNRA (0.62) | EDNRAEDNRBDHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012056468-A1 | A PROCESS FOR THE PREPARATION OF BOSENTAN | MATRIX LABORATORIES LTD (IN) | 2012-05-03 | — | — | WO | disclosed |